After researching hundreds of brands, buying, trying and reviewing dozens of CBD oils, it is safe to say the ABC's of CBD are still being spelled out. A smart buyer's guide is essential.

CBD is now the most recognized naturally-occurring cannabinoid found in hemp, setting the cannabis culture ablaze for its potential medicinal benefits and potent therapeutic effects.

The highly-touted CBD extract from the cannabis sativa plant has admirable associations for being a safe, non-habit forming solution to helping a myriad of different health conditions.

The prominently-prized cannabidiol compound is poised to capture an unprecedented portion of global nutraceutical and pharmaceutical formulations. And it does not make you ‘high’ like its notorious psychoactive cousin-cannabinoid, tetrahydrocannabinol (THC).

While CBD may be akin to the yang to THC's yin, the non-intoxicating phytocannabinoid is truly trailblazing its own path. Once the 2018 Hemp Farming Bill enactment, CBD products under the 0.3% THC threshold soared due to removal of its Schedule I status on the Drug Enforcement Agency's (DEA) Controlled Substance Act. This regulatory milestone greenlit hemp CBD's legal gateway, spawning a new era of CBD-infused supplementation.

The United Natural Products Alliance reported over 1,500 hemp-derived cannabidiol oil products are now available since 2016. The UNPA President did share his amazement on the CBD craze, saying, “I’ve never seen a market like this in my nearly 40 years in the industry.”

There are over 1.2 million CBD users in the United States (58% women) and 41% are active daily consumers. Unfortunately, due to off-the-chart interest and an overwhelming variety of CBD products to choose from, the wild-wild-west pioneering days of the market has brought its fair share of snake oil sellers to the surface. It is a 99.9% absolute-must have to utilize a savvy shopping strategy checklist when buying the best CBD oil supplements.

The highest hope here is to help educate users and inform buyers on which quintessential qualities matter the most. Instead of rushing through some ‘half-baked' review rubbish of, “you ought to try some CBD for that”, this user-first research guide focuses on a CBD company's onus to prove their product's remedial effectiveness. A brand's authority and credibility is bound to making quality a priority via documentable purity and potency.

Before unveiling TimesofCBD research team's coveted 2020 best CBD oil products and top cannabidiol-branded companies rankings list, here's an insightful index to bookmark-worthy analysis designed to enhance user awareness and purchasing power:

CBD, as they say, is happening; and CBD is Cannabis' Big Deal hemp ingredient being hailed as a homeostasis healer, backing a bold $22 Billion industry forecast by 2022.

However, as the CBD market stands today, no quality control measures are standardized. This puts users at real risk. Yet, consumers don't have to face the unknown alone.

Thankfully, identifying key metrics can help extract a stronger signal from the nauseous noise involved when unmasking the nascent stages of the emerging CBD space.

Step one is of paramount importance, acknowledging how each of these product features and company metrics stack up in comparison during a pre-FDA approved timeframe.

No matter what health goal or cause of concern, using a buyer-beware questionnaire seeking answers to the who, what, when, where, why and how diagnosis will help prepare caring customers looking for a reputable product by a respected brand. The ‘devil is in the details'.

Acting vigilant helps avoid unnecessary hardships in a dangerously underserved and unregulated sector. Stick to a cautiously optimistic approach and weed out the bad actors.

Choose a congruency-centric CBD company who upholds strict product sourcing protocols and rigorous testing procedures. Otherwise, it's difficult to fault the lack of user results.

Additionally, Brightfield Group, the same company who predicted the CBD marketplace to blossom into a $22 Billion business sector by 2022, shares a visual graphic indicating what users value most between CBD (cannabidiol) and THC (tetrahydrocannabinol) cannabinoids:

Debatable and even controversial, CBD “OILS” are thought to offer the most bang for the body; factoring in efficacy, potency, bioavailability, price per serving, and deliverability.

However, all users should know there is no-1 CBD oil size, kind or cost that fits all. The secret sauce to a CBD product and company research guide is sifting through sparse science and unearthing the ‘best of' attributes which superior-quality canndbidiol oils should carry.

The chopping block starts in distinguishing the various types of CBD oil specifications. Before analyzing a company’s COA (certification of analysis) and some semi-standardized soil and seed product sourcing claims containing no verifiable third-party lab tests, step two is clarifying the differences of hemp-derived CBD and CBD with THC.

Also, note the hemp oil vs CBD oil differences because the terms should not be used interchangeably. Pure hemp oil is derived from hemp seeds and phytocannabinoid-rich CBD comes from hemp plant's essential oils derived from the flower, leaves and stalks.

Extensive one-on-one guideposts for each variety is covered in the FAQ below, but the top 30 CBD oil products are a methodological mix of the top three types.

First, a quick snapshot highlighting a brief overview of CBD, followed by the best cbd oils list. Then a complete guide on the best CBD oil-infusion product types.

Each of these consumable options are enticing ways to use cannabidiol. But, not all CBD product types work the same. To be fair, there's many polarities to compare and contrast.

It can be a daunting, deep-dive decision into the cannabis oil abyss, but the most common use case involves oils/tinctures and edibles by a wide margin in popularity and sales.

Topicals (skincare), inhalables (smoking), pets (dogs/cats) and pharmaceuticals (‌Epidiolex) are all novel treatment applications with rising interest (each offering their own distinct effects and benefits), but CBD oil has more well-received notoriety.

While debatable and even controversial, CBD “OILS” are thought to offer the most bang for the buck; factoring in price per serving, deliverability, bioavailability, potency and efficacy.

Without covering the history of CBD in great depth, and elaborating on the isolate, broad and full spectrum CBD oil variations touched on above, the next phase is to know CBD originates from two varieties of cannabis; hemp and marijuana.

Industrial hemp and marijuana are from the same plant family species, but vary genetically like a cousin. In a nutshell, CBD is known as a 21-carbon terpenophenolic substance made by using a decarboxylation process from a cannabidiolic acid precursor that was discovered in 1940 and is one of 113 identified phytocannabinoids.

Because CBD (and THC) constitutes 2-5% of the plant's medicinal value, (which is significant in comparison to other popular cannabinoids like cannabigerol (CBG), cannabinol (CBN), tetrahydrocannabinolic acid (THCA), cannabichromene (CBC), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), cannabigerolic acid (CBGA) and cannabidiolic Acid (CBDA)), the boastful ‘newness' of this hemp-derived cannabis oil extract as a true wellness catalyst is growing rapidly because of its versatility and non-abusive potential to cause harm.

Tieing in the CBD oil types, studies show the ‘entourage effect' of cannabinoids found in full-spectrum CBD oils may be optimal intake (avoid THC if have drug testing obligations) due to the basic botany and cannabinoid pharmacology working cohesively together. While stilll largely under-studied and clinically validated, user should take upfront accountability in knowing all CBD oils are not created equally.

This immensely-high CBD cannabis oil emergence is sparking a revolution within the marijuana movement, and even though CBD may not be the cure-all panacea many would love to claim, the attractive affiliations with pain relief, anxiety/stress, skincare and sleep recovery are adding up overtime. However, a plethora of problematic concerns arise and must be addressed accordingly as a whole.

As Pal Pacher, International Cannabinoid Research Society President and National Institutes of Health investigator put it:

“it's scary… [adding] consumers are participating in one of the largest uncontrolled clinical trials in history, and no one really knows what it is they're taking”.

“The science is lagging behind the public use and interest. We’re doing our best to catch up here.”

Even a physician and pharmaceutical researcher, as well as teacher at the University of Miami Medical School added:

“the quality control and regulatory oversight for CBD is not much beyond what it is for Snickers bars.”

Then Harvard Medical School medicine instructor and Association of Cannabis Specialists President put it:

“CBD is being used over the counter in a range of ways that is not supported by the science,”[…] “There is still much we don't know. But aggressive marketing, hype, and word of mouth have made CBD like a drug version of the emperor's new clothes. Everyone says it works, but lab studies suggest that it's really not what people think. ” […] The main problem is that not enough medical studies have been done to offer any kind of clear guidance, and a lot of health claims can probably be attributed to a placebo effect, meaning companies can put out all kinds of CBD products with zero accountability.”

Which is the perfect transition into the hidden hurdle of the last mile details, distilling down into a company's transparency of verifiable product testing results.

Hemp is a bioaccumulator, soaking up all the surrounding heavy metals, pesticides and toxins found in the soil and water. It is imperative to know where a company's hemp-derived CBD oil is sourced from and how high farming and manufacturing standards are upheld. CBD companies with independent lab-backed auditing and certification of analysis (COA) that provide requisite safety data of appropriate third-party toxicological assessments will be crowned and championed in a crowded CBD market.

While botanical and nutritional medicine is barely over a century old, the following CBD companies are well under a decade in age, yet the ‘green rush' is happening right now.

Being a educated buyer comes from being an informed user. Even if a company has the ‘know, like and trust‘ factors in its favor, it may not paint the entire picture given the hyped-up magnitude of hemp's hysteria as a whole. The real stems and stones lie within critiquing company-specific caveats in great detail by dialing in on key optics to evaluate and examine.

The high-CBD cannabis oil industry is far from adopting voluntary standards to self-regulate. Thus a ‘proof is in the CBD pudding' approach is born to debunk dubious, egregious and unsubstantiated claims. Be inclined to lean on the side of skepticism.

Because there are hundreds of competing brands all extolling the supposed virtues and endless possibilities for CBD, it's time to separate fact from fictional folklore fantasy.

In order to confidently-conclude which CBD brands offer the highest-quality products, a significant amount of upfront research is required to compile a comprehensive meta-rank list. From the intro to the outro, the long-winded focus put forth was on the onus of a company's ‘proof of pudding' for each of their CBD products ‘remedial effectiveness'.

Hemp is a sequestrator of all the things in the environment as the crop is known for bioremediation, meaning if the hemp is planted in a contaminated area, it would soak up all the contaminants in the ground's soil. This translates into a woeful waste of cannabidiol-rich oil when extracted, even if it gets purified it could still be brimming with impurities.

Due to forming regulations and modern-day low barriers to entry, coupled with the absence of clear-cut FDA regulations and guidance for hemp-derived CBD manufacturing, no industry-wide quality assurance metric or testing protocol is set in stone to keep all of these brands in check. Combined with much of the commentary on CBD is dominated by promoting and promising their product line to the highest of heavens. As stated above, it is safe to say not all CBD oils, tinctures or products are created equally let alone rigorously.

As the budding cannabis oil market unfolds, a need for researching optimal growing conditions (product), honest business transparency (company) and overall reputation practices (brand) lies at the heart of this dedicated due-diligence guide. By shining a spotlight on the soil of how each company's product line is grown and avoiding watered-down ‘review recommendations', it's easier to shift the emphasis to the heartbeat of the matter. Getting acquainted with a brand's quality control measures will highlight the attention, care and ultimately love baked into each step of the CBD pudding's recipe. From seed to sale, this is the best way to get the biggest bank for the buck bar none.

If CBD is going to provide any beneficial effect at all, its purity, potency and pricing metrics must match up first no matter what CBD-infused administration is tried. From gummies, edibles, drinks and beverages, skincare, vapes, topical balms/salves, softgels or even flower buds; knowing the integral intricacies of a CBD company's product is indispensable.

The ratings below are calculated and sourced using over a dozen different data points. The most popular and actively-referenced companies in the marketplace today all deserve quick fact summaries about their location, hemp source, lab-tests, association connections, different-strength CBD oil dosage options and full array of product infusion types offered.

Each brand's brief bulletpoint breakdown gives all of the top-level criteria pertaining to every CBD company. This is no small feat to formulate, but considering what is at stake (your health, well-being and livelihood), it is a very important mission to undertake.

While some fundamental elements were referenced in the product vs company metrics table above, we averaged all factors into a single five-point score (last updated September 2019).

While this is far from a lecture, the lesson is do not be misled by cheaper prices or dosing inconsistencies. Do not buy into the marketing gimmicks of a random brand pretending to create competitive advantages or think because a specific company has a bigger marketing budget or advertising prowess to gain a larger social media following that they are magically better than the rest. As the US Hemp Roundtable General Counsel put it best:

“The biggest challenge in our industry isn’t the DEA, the FDA, or the USDA,” […] “It’s the companies that are selling CBD improperly and making medical claims.” […] “We’re doing everything we can to expedite [the FDA regulations for CBD] because we’re all very anxious about getting a regulatory pathway for the recognition of CBD as a dietary supplement and a food additive.”

And Dr. Jordan Tishler, cannabisMD medical advisory board member and Association of Cannabis Specialists President said:

“Unfortunately, most of these sources are unregulated…this means that if you’re not careful about where you’re buying CBD from, you may actually be buying a product that contains little or no CBD at all.” […] Many over-the-counter CBD products contain no CBD, or worse, may have dangerous ingredients in them like heavy metals or opiates.”

Unfortunately is right, due to limited regulatory oversight in a flooded CBD marketplace, colossal causes for concern arise regarding optimal purity and overall quality given the sheer amount of products offered online or in local health food stores, coffee shops and even corner stores. From mislabeling risks to the lack of inadequate laboratory controls who do not abide by GMP (Good Manufacturing Practices) or third-party audited facility processes, the stakes are now truly higher than ever for researching WHO is responsible for each CBD product up for buying consideration. It is absolutely in everyone's best interest to ask the who, what, when, where, why and how questions if contemplating whether or not to spend hard-earned money on trying a CBD-based health regimen.

Dr. Ethan Russo, International Cannabis and Cannabinoids Institute research and development director, chimed in with:

“And it’s these easy access options, such as online retailers and even gas stations, touting CBD products that often leave people skeptical of it. But that shouldn’t necessarily be the case either.” […] “It's easy to say because of the profusion of [CBD on the market] that it's all witchcraft or snake oil, but that’s not the case.” […] “CBD is a very versatile medicine that hasn’t gotten the attention it deserves over the decades.”

“Because of the non-FDA approval, anyone can open up a CBD store and process it and try to sell it for a profit, and that’s what’s happening right now.”

Listen up. The “Total Cannabinoid Market” (TCM), which encompasses all recreational and medical cannabis sales in licensed dispensaries (even combined with FDA-approved pharmaceuticals and hemp-based CBD products), is predicted to hit $15 billion in 2019 and surpass $40 billion by 2024. As stated, the green rush is upon us and these top CBD brand ratings will be continuously updated as new information and feedback becomes available given more insights and research. The most professional companies are helping advance the CBD conversation and acquiring proper awareness and education is vital for everyone as the hemp-CBD market blossoms into the $22 billion dollar market in the next three to five years.

The foreseeable future of CBD is bright and every company overview is laced with easy-to-digest bite-sized nuggets on the nitty gritty details, as well as a link to the official website and full CBD brand review.

Charlotte’s Web is a high-quality source of CBD products that is well-known for the wide range of tinctures they offer. Charlotte’s Web regularly dominates international CBD rankings. The Charlotte’s Web range is made in its entirety in Colorado, and is developed by the Stanley brothers — a family of seven brothers that live in the state.

All of the products offered by Charlotte’s Web are completely natural, and use a non-psychoactive source of CBD-rich hemp in the manufacturing process. The wide range of products offered by Charlotte’s Web also makes it ideal for individuals seeking specific, targeted CBD solutions.

Charlotte’s Web is highly transparent in the way they label and advertise products, and offers a detailed frequently asked questions page that delivers insight into the way their products work and what they do.

Medterra manufactures and offers a range of different CBD oils and tinctures that are created in Kentucky, from hemp grown in Kentucky. Interestingly, the hemp that Medterra products are created from is grown to meet the standards of the Kentucky Department of Agriculture, and thus contains a 99% or higher ratio of CBD to THC.The hemp used in Medterra products is non-GMO, and is independently tested by third party laboratories in order to ensure that it meets stringent Medterra standards. Medterra follows a policy of transparency in delivering their products, and offers insight into the specific dosage levels of the products they sell.

Medterra is able to sell their products in 50 states within the US and a number of international countries due to the high standards they follow and the strict CBD isolates they provide.

CBDistillery offers a diverse range of CBD products that includes CBD oils and CBD tinctures, as well as full-spectrum options and pure isolate CBD products. Importantly, all products sold by CBDistillery are independently tested by a third-party laboratory, the results of which are available publicly for each individual product.

CBDistillery uses non-GMO plants in the extraction process that creates their CBD range, as well as hemp that is free from pesticides or other chemicals. While CBDistillery goes to great lengths to ensure that their products are natural, they are not currently certified as organic by the USDA.

The CBDistillery website notes that each individual has individual needs, and thus recommends that users select the right CBD product for them after consultation with a medical professional.

Lazarus Naturals offers a diverse range of CBD products, and is one of the only CBD suppliers that uses Kosher alcohol in the purification and distillation process used to extract the cannabidiol from the high quality hemp used in the creation of their products.

Lazarus Naturals products are all independently tested in third-party laboratories in order to ensure they are of the highest degree of quality, and are completely free from pesticides and heavy metals. Lazarus Naturals products do contain trace amounts of THC, however, which precludes them from sale in some US states, but still contain less than the 0.3 percent of THC dictated by the US government.

The cbdMD brand is based in Northern Ireland, but obtains CBD-rich hemp from a private grow facility based in Colorado, US. The hemp grown by the Colorado operation used in the cbdMD product line is cultivated in a nutrient-rich soil base fed by both the Mississippi river and the Kentucky river.

cbdMD products include 300mg and 3000mg tinctures in a variety of different fruit and citrus flavors, and contains A-grade cannabidiol that is considered extremely high spectrum and includes CBG, CBDV, and other cannabinoids.

cbdMD tinctures also contain amino acids and natural essential oils in order to enhance bioavailability and increase overall health benefits.

CBDPure is owned by the Nutra Pure Corporation, a leading provider of natural health products that is based in Vancouver, Washington. The CBDPure range consists of many different types of CBD health solutions, and as their products contain no CBD, CBDPure has been able to expand internationally into the UK.

The most popular products offered by CBDPure include formulas that range in potency from 100mg to 650mg, with organic hemp extracts combined with completely natural flavors. Rather than focus on specific medical conditions, CBDPure products are designed to deliver an overall health boost that maximizes the generalized health benefits of cannabidiol

Based in Daviel, FL, Green Roads is a market leading provider of CBD products sourced from Colorado-grown hemp. The Green Roads range consists of a selection of CBD oils ranging from 250mg to 3500mg, with customer reviews stating that their products assist with anxiety, sleep disorders, inflammation, joint pain, and other issues.

In addition to CBD oils, Green Roads offers terpenes, topical solutions, concentrates, capsules, edibles, coffee, tea, and even CBD pet products. All of the products in the Green Roads range are independently tested by a third party, with lab results posted on the Green Roads website.

Green Roads also operates a non-profit organization called Mission Zero, which aims to assist veterans suffering from the symptoms of PTSD and is specifically focused on minimizing veteran suicide.

CBD American Shaman is a franchise organization with locations across the entire united states, and thus uses a variety of different hemp sources. All of the hemp used in the creation of CBD American Shaman products are based in the US, however.

All CBD American Shaman hemp sources are gluten free, organic, and non-GMO, with CBD extracts backed up by clinical laboratory tests that involve ultra performance convergence chromatography. The full spectrum CBD oil offered by CBD American Shaman is one of the most powerful options available on the market, and is 10 times more bioavailable than traditional CBD oil solutions.

CBD American Shaman also provides discounts to veterans as part of a robust compassionate care program.

CBDMEDIC, made by Abacus, is a family of over-the-counter pain relief medications designed to provide relief from minor pain. The company uses a proprietary formula to bring safe, fast, and powerful pain relief through the use of ointments, creams, sprays, solid sticks, and massage oils. They also offer a lineup of skincare CBD products, including eczema therapy, acne creams, and itch and rash relief creams.

CBDMEDIC claims their topical medications are formulated with authorized pharmaceutical active ingredients to safely and effectively target pain at the site of the discomfort. In that sense, they’re not “just another” CBD topical. Plus, the naturally-derived essential oils, emollients, and extracts can be combined to create a “synergy effect”, according to the company. In addition to CBD, these products contain ingredients like menthol, camphor, jojoba seed oil, eucalyptus oil, peppermint oil, and clove oil, among others.

CBDMEDIC was founded in 2017, although the company claims their team has 15 years of pharmaceutical and skincare experience specializing in natural ingredients. In 2019, CBDMEDIC partnered with former NFL star Rob Gronkowski, and Gronk is now featured prominently in the company’s marketing

Sunday Scaries claims anyone can beat the Sunday scaries with their high-quality CBD products. The company is best-known for its gummies and candies. However, they also cell CBD oil and CBD bath bombs, among other unique products. The company’s bundles are also popular – especially if you’re just getting into CBD for the first time and want to see which option you like best.

Sunday Scaries claims their products are made with the highest quality broad spectrum CBD sourced directly from family-owned hemp farms in Colorado. In addition to broad spectrum CBD, some of the Sunday Scaries products include vitamin B12, vitamin D3, coconut oil, and organic stevia, among others ingredients.

The company uses a unique approach to marketing and branding that immediately distinguishes itself from the competition. From the colorful CBD bath bombs to the distinctive “Yolo Shot” CBD energy shot and “Unicorn Jerky” CBD candy, Sunday Scaries’ lineup of products has carved a unique niche among CBD fans.

Bluebird Botanicals is the highest ranked CBD provider in our meta-study, and provides a range of full-spectrum CBD oils derived from Colorado-grown hemp. Colorado hemp is one of the highest quality sources of CBD in the world, and is able to deliver over 80 different phytocannabinoids.

Bluebird specifically uses varieties and subspecies of Colorado hemp that contain very low levels of THC, and thus are able to offer products that have no psychoactive properties. Importantly, Bluebird Botanicals is highly transparent in the way they package, label, and advertise their products.

Bluebird Botanicals also practice responsible CBD delivery, recommending that customers consult with a medical professional before beginning CBD dosing, and do not make any specific health claims regarding their product.

Based in Norwalk, CA, Koi CBD is a top-notch provider of extremely high-quality CBD products that are manufactured via an precise and transparent methodology. The hemp used to create the Koi CBD range is grown in the San Luis Valley.

Koi CBD is backed up by a large number of customer testimonials that attest to the efficiency their product range is able to assist with a wide range of health disorders that include inflammation, depression, neurological conditions, chronic pain, and more.

The Koi CBD product range is proven to contain pure CBD extract by third party laboratory tests, which are published on the Koi CBD website. The large amount of positive feedback for Koi CBD makes it one of the top 10 CBD suppliers online.

CBDfx is another high-quality CBD product provider that uses hemp sourced in Europe to create their range. Offering a selection of CBD tinctures and other products, CBDfx delivers a range of solutions that can be used to assist with a wide range of health conditions that include sleep disorders, chronic pain, inflammation, and more.

All of the products offered by CBDfx, which include CBD wax, CBD tinctures, CBD pet products, CBD gummies, CBD vape pens, CBD chill shots, and CBD oils have all been lab tested, with full lab analysis available on the CBDfx website.

CBDfx also provides a glossary of terms that can help simplify learning about CBD, as well as providing information about the benefits, compounds, and best practices for using CBD.

PureKana Natural CBD Oil is based in Scottsdale, AZ, and is a highly competitive brand that offers a number of unique products. The PureKana Natural CBD Oil manufacturing process results in high-quality CBD products that are available in most states, as PureKana Natural CBD Oil products do not contain THC.

The PureKana Natural CBD Oil product range includes tinctures, edibles, topical treatments, and oils, and are all created from naturally-grown hemp plants from grow operations based in Kentucky. Each individual PureKana Natural CBD Oil product is subjected to analysis and quality control, with third-party lab tests on the PureKana Natural CBD Oil line available to consumers.

Based in Conway, SC, Palmetto Harmony uses natural hemp grown in Kentucky in the extraction process for the range of CBD products they offer. Interestingly, the Palmetto Harmony Kentucky hemp growing operation is run under a federal government agricultural program that operates in compliance with the 2015 Federal Farm Bill.

The Palmetto Harmony blog provides a long list of success stories provided by individuals using their products, with use cases involving the treatment of anxiety, PTSD, and depression. The state-owned source of hemp used by Palmetto Harmony makes it possible for consumers to request laboratory testing results on the organic matter used to create their line on request.

Palmetto Harmony has an interesting founding story — the owner of the company began using CBD products to treat a family member’s health conditions and, after observing the powerful health benefits CBD products offer firsthand, launched the Palmetto Harmony company.

NuLeaf Naturals, based in Denver, focuses specifically on the creation and distribution of CBD tinctures that can be taken orally or applied topically to the skin. There are a wide range of uses for NuLeaf products, all offering health benefits such as decreased inflammation, improved mood balance, and better immune system function.

NuLeaf Naturals develops and manufactures their product line in Berkeley, California, and provides customers with extensive documentation captured during third party testing of their products and CBD extracts in order to deliver transparency and honesty.

Diamond CBD maintains an international base, with offices in both Florida and Manchester in the UK. The CBD used in the creation of the Diamond CBD range is extracted from plants that are grown without the use of pesticides, GMO products, chemicals, or artificial fertilizers.

The Diamond CBD range comes in both natural and flavored options, and is backed up by extensive public third party laboratory testing results. Customer reviews of Diamond CBD products state that they are able to deliver relaxing, anti-stress, and chronic pain management benefits.

Joy Organics is a Colorado-based CBD and hemp company offering a wide range of products across the United States. The company’s products include tinctures, softgels, salves, vape pens, energy drinks, pet products, and CBD gummies, among others.

Joy claims to use a seven step process to create the highest quality CBD possible. Each Joy product starts with proprietary, high-CBD strains of hemp grown in the United States. Then, the plants are dried and milled into a coarse powder. Joy uses a proprietary hemp extraction and purification process that involves supercritical CO2. This process creates high quality broad spectrum hemp oil. Minute traces of THC are removed from the oil, then the oil is sent to a third party lab for testing.

Joy Organics claims their softgels have several unique advantages over the competition. Joy uses proprietary “nanoemulsion” technology to formulate its softgels. This makes the softgel formulas at least twice as bioavailable as oil-based products. While competing hemp oil particles are between 100 and 1000nm in size, Joy’s particles are around 25nm. “This small size leads to much more effective absorption”, according to Joy Organics.

CBD Living uses a wholly unique extraction method developed by a team of international scientists in the manufacturing process used to create their product line. This method, which involves the application of nanotechnology on a microscopic scale, reduces the size of CBD droplets into nanoscopic size, which dramatically increases bioavailability.

The nanotechnology used in the CBD Living manufacturing process can enhance the bioavailability of the CBD products they offer by 90%, making their product line almost twice as effective as normal CBD offerings. CBD Living offers CBD-infused water as well as capsules, patches, gummies, soaps, and bath bombs.

Plus CBD Oil is a hemp derived CBD oil brand from CV Sciences. The San Diego-based company offers a full range of CBD products, including sprays, drops, roll-ons, gummies, capsules, and softgels. CV Sciences also claims to be the biggest manufacturer and distributor of wholesale hemp oil in North America.

Balms are available in original and extra strength varieties. You apply the balm to your skin for moisture. The CBD oils, meanwhile, are available in unflavored, peppermint, and café mocha varieties. Just spray twice in your mouth, hold for 30 seconds, then swallow. 100mg and 500mg concentration are available in 1oz or 2oz bottles. The Plus CBD Oil roll-on product includes CBD mixed with camphor, a warming agent, which boosts circulation and increases topical absorption. The Plus CBD Oil softgel capsules, meanwhile, come with 15mg of CBD per softgel capsule and are made with an extra virgin olive oil base.

As with most other CBD producers, CV Sciences uses CO2 extraction and a chemical free extraction process to create high-quality, pure, and safe CBD oil. All products are also laboratory tested both in-house and via a third party lab. CV Sciences uses a traceable supply chain process called Seed to Shelf, making it easy to track the CBD product at every step of its development

Populum is a provider of top CBD oil solutions derived from hemp grown in Colorado. Based in Tempe, AZ, Populum supplies some of the highest-rated and reviewed CBD oil product in the United States. Customer reviews of Populum products indicate that their range of CBD oils is highly effective in treating a range of illnesses that include anxiety, joint pain, chronic pain, and panic attacks, as well as migraines.

Populum, like other respected CBD suppliers, offers detailed independent laboratory analysis results of their products but makes lab results available for products on an individual basis. A unique difference between Populum and other CBD suppliers is the 30 day trial period they offer for new customers who are trying to decide whether CBD is right for them.

Good Vibes is a subsidiary of natural health company Sabaidee, which focuses primarily on customer satisfaction above all. The Good Vibes product range is backed up by a 100% customer satisfaction guarantee, and consists of a range of different potency CBD extract.

A unique point of difference between Good Vibes and other CBD brands is the Good Vibes promise to plant one tree for every bottle of Good Vibes CBD oil tincture sold, working toward a more sustainable CBD sale framework

Sol CBD is one of the only CBD manufacturers and suppliers that uses advanced CO2 extraction techniques in order to create extremely potent and effective CBD products. The processing facility used to create Sol CBD products is GMP certified and has been registered with the FDA.

Sol CBD is specifically focused on offering CBD health products that enhance the quality of life for individuals that suffer from chronic health conditions, and can assist with the management of chronic pain, anxiety, PTSD, and sleep disorders.

All of the Sol CBD products are accompanied by independent third party lab tests.. Importantly, Sol CBD offers a 100% customer satisfaction money back guarantee for 60 days.

Endoca maintains a presence in both San Diego, CA, and Hoofddorp, in the EU. This dual location foundation allows Endoca to use extremely high quality certified GMO free and organic hemp grown in the EU in the creation of their CBD products.

Endoca doesn’t provide explicit health guidance on how to use their products, but does offer an excellent and informative database that covers the clinically proven benefits of cannabidiol and CBD products that include inflammation management, assistance with seizures, sleep relief, pain relief, and psychological benefits.

The Endoca team also engage a laboratory team in order to perform a broad range of lab tests on their product, including NMR and HPLC tests to make sure that the consumers that use Endoca products are getting the highest quality CBD available.

Importantly, Endoca products are also made pesticide-free hemp. The stringent quality control offered by Endoca, paired with their high-quality knowledge base, makes Endoca an industry leader in CBD products.

Fab CBD was founded on a single concept- to redefine the way holistic health and natural health solutions are perceived and used by the world at large. To achieve this, Fab CBD uses the highest quality hemp available in Colorado to create extremely effective high quality CBD products backed up by accredited laboratory testing results.

Fab CBD focuses on increasing the availability of effective natural health solutions, and offers naturally flavored CBD supplements that are created without the use of pesticides or chemical fertilizers. Fab CBD products have been reviewed to by customers to be extremely effective in assisting with back pain management, and are backed up by a 100% satisfaction money back guarantee.

One thing that separates Santa Monica-based Sagely Naturals from its competitors is the way it brands and markets its products. The company offers a series of CBD ‘Collections’, for example, including their ‘Relief & Recovery’, ‘Tranquility’, ‘Extra Strength’, and ‘Drift & Dream’ collections. The Relief & Recovery collection, for example, includes a cream, capsules, roll-on, and spray priced between $20 and $50 apiece.

Another thing that differentiates Sagely Naturals is that the company doesn’t sell CBD oil. The company only sells creams, capsules, roll-ons, topical oils, and sprays. Dosages are also a little lower than what you might find with other CBD brands. The capsules, for example, contain 10mg of CBD apiece for 300mg of CBD in each $50 bottle. The Extra Strength Relief & Recovery capsules, meanwhile, contain 20mg of CBD per capsule and 600mg of CBD in each $75 bottle.

Overall, Sagely Naturals emphasizes high-end formulation and superior absorption. The company’s formulas were created by PhD chemists, and Sagely manufactures its CBD in state-of-the-art facilities with premium hemp grown in the United States

HempMeds is a subsidiary of Medical Marijuana, Inc. In January 2019, HempMeds made waves in the CBD industry when it announced the launch of its maximum strength full spectrum hemp oil with an impressive 45% CBD content. Today, HempMeds continues to sell its popular Real Scientific Hemp Oil Max Strength (abbreviated to RHSO Maximum Strength), and the company claims that its “the most potent CBD product per serving size” available through the Medical Marijuana Inc. family of companies.

Each 10g oral applicator includes 4500mg of CBD, and you get 225mg of CBD in each half gram serving. The formula also contains both CBD and the raw form of CBD, CBDa. You can take the product by spoon. Or, you can apply it sublingually by placing the oil under your tongue and holding it for one minute. Some even put the oil into an empty capsule, then take it as you would take any capsule or pill.

Medical Marijuana, Inc. was the first company to bring hemp-based CBD oil products to market in the United States all the way back in 2012. They were also the first publicly-traded cannabis company in the United States in 2010. Today, they’re continuing that legacy under the HempMeds brand. Other companies in the Medical Marijuana, Inc. family include Kannaway, HempMeds Brasil, and HempMeds Mexico.

RE Botanicals is a hemp and CBD oil company offering a small selection of tinctures, CBD oils, and capsules. The company claims to have been the first national brand to sell U.S. grown, USDA certified organic hemp. Unlike many other CBD oil companies, RE Botanicals uses alcohol processing instead of CO2 processing. Alcohol processing is the centuries-old way of extracting active ingredients from hemp, although RE Botanicals uses organic cane alcohol “for a modern take” on the age-old processing technique. Then, the company blends its hemp extract with MCT oil, packaging it all at a USDA NOP certified facility.

RE Botanicals was created by John Roulac, who founded organic superfoods brand NUTIVA in 1999. The company sold hemp bars among other natural health food products. In 2018, John founded RE Botanicals, giving the company the tagline “the pure organic hemp apothecary.” The company is registered in Hamburg, Germany under the name RE Botanicals, Ltd., although all company products are grown and made in the United States.

Today, the RE Botanicals online store sells a range of tinctures, topicals, capsules, CBD pet products, and more. The company’s USDA organic certified, full spectrum CBD oil in MCT oil is particularly popular, available in both peppermint and natural flavorings. You can buy it in dosages of 450mg ($50), 750mg ($75), or 1,500mg ($136).

Premium Jane’s hemp is grown and harvested organically in Oregon and formulated in Michigan. The hemp is processed using solvent free CO2 extraction, extracting the hemp molecules in a low-temperature, high-pressure setting.

Today, the company offers a full range of CBD oils, capsules, topicals, and gummies, including oils in citrus, mint, or natural varieties. Dosages range from 300 to 1000mg for the oils, while the gummies and capsules have 25mg of CBD in each piece. Premium Jane also offers a 1500mg topical location that they claim is “the most potent CBD cream available outside the medical cannabis market.” The topical location is available in cocoa butter (1500mg) and eucalyptus (750mg) options.

Premium Jane also began shipping products to the UK in June 2019. All products are available for purchase through the Premium Jane online store and through other online retailers. Overall, Premium Jane is a relatively new member of the CBD scene, but the company is doing everything right to continue dominating the market in the future.

Green Gorilla operates multiple locations in Los Angeles, Malibu, Sao Paulo, and London, making it a powerful international brand. The extraction process used to create Green Gorilla products is completely chemical-free, and results in a product that is completely free from THC.

The CBD tinctures available from Green Gorilla come in full-spectrum and isolate form, and are reported in customer reviews to assist with the reduction of inflammation, anxiety, stress, depression, and chronic pain. The hemp used in the Green Gorilla product line is GMO-free and sourced from whole plant phytocannabinoids, making it an extremely popular option.

Ignite offers a range of CBD products, although they’re best-known for their CBD vape pens and CBD oil drops. Ignite sells rechargeable vape pen starter kits for $50 to $60, with disposable vape pens priced at around $45. The company has partnered with Bo Vaping to offer the best-quality CBD vape pens. You can buy the vape pens in flavors like ‘spearmint’ and ‘pink chill’. The CBD oil drop, meanwhile, are priced between $60 to $70 and come in tropical fruit, lavender, and blood orange varieties, among others.

In addition to vape pens and CBD drops, Ignite offers a product few others offer: CBD toothpicks. There’s 25mg of CBD per toothpick, and you just chew on the toothpick to get the powerful effects of CBD. CBD gets released into your gums and sublingual cavity, allowing you to enjoy the effects of CBD in a unique way. The CBD toothpicks are available in flavors like menthol, cinnamint, mango mint, lemon grass, and coffee.

Ignite only ships to the United States. The company does not ship to Idaho, Nebraska, Ohio, and South Dakota. If you’re looking for some of the best quality CBD vape pens (rechargeable or disposable) or CBD oils, however, then Ignite is one of the best options available today – although the company does not claim its products undergo any type of lab testing.

Kat’s Naturals offers a broad range of CBD products created from Tennessee-grown hemp. The tincture available from Kat’s Naturals contain 99.9 percent CBD, and are combined with a broad spectrum of organic essential oils such as ginger, peppermint, and lemon in order to deliver a wide range of additional health benefits.

Kat’s Naturals product line is complete with suggestions for use that indicate Kat’s Naturals products may be able to assist with inflammation, depression, and anxiety, among other health benefits. Like many other industry-leading CBD suppliers, Kat’s Naturals products are subjected to third-party laboratory analysis.

Kat’s Naturals also provides a very clear explanation of the manufacturing methods used to create their line of products, which include CBD oils and CBD tinctures.

Hemp Bombs is based in Manchester in the UK but uses hemp grown in a variety of international locations including the United States in the manufacture of their product range. The Green Bombs range of products sold by Hemp Bombs can be used for a broad range of conditions that include PTST, fibromyalgia, insomnia, inflammation, and seizures.

Hemp Bombs follows Indiana state compliance law in their labeling process and makes all independent third party lab testing results available via their website. The Hemp Bombs website also provides consumers with a massive database of information regarding the health applications and manufacturing process of CBD tinctures, CBD oils, and the other products they sell. A video gallery also makes learning about the health benefits of CBD easier for individuals new to the world of CBD health benefits.

Select CBD is a popular CBD brand from Cura Cannabis Solutions. The company’s CBD is extracted from industrial hemp – just like most other CBD companies available today. You can buy Select CBD Drops, which give you CBD in tincture form, or you can buy the Select Blends disposable vape pens for a convenient vaping experience. There’s also a full lineup of Select Oil THC products (available in states where recreational cannabis use is legal), gel capsules, and more.

Select is known for its proprietary blends that combine pure CBD isolate with a range of carefully chosen essential oils and herbs. You can get CBD on its own. Or, you can buy a CBD blend where ingredients “work synergistically to maximize all potential benefits”, according to Select CBD’s official website. Unique flavors like lavender, lemon ginger, and peppermint are all available, although you can also purchase unflavored varieties.

Select CBD has won a few notable awards over the years. They were picked as Leafly’s Best in State for Best High CBD Product in Oregon, for example. Select CBD’s parent company, Cura Cannabis Solutions, was also #1 on the Inc. 5000 list for the Portland, Oregon metropolitan area, #1 on the Inc. 5000 list for “Top Oregon Companies”, and #4 on the Inc. 5000 list for “Top Consumer Products & Services” company. They were also picked as one of the Top 100 Companies to Work For in Oregon in 2018.

Xwerks distinguishes itself from other CBD companies by marketing its products mostly to fitness enthusiasts. The company’s website is filled with images of tattooed Crossfitters taking the company’s products while throwing around weights. While other CBD companies emphasize chilling and relaxing, Xwerks advertises their products as an effective way to complement your workout and recovery.

Xwerks makes it simple when it comes to consumer choices. The company offers just two CBD products, including Xwerks CBD Oil and Xwerks CBD Oil Softgels. The Xwerks CBD Oil is available in one size (600mg) and costs $69, while the softgels are available in one size as well (750mg). There’s 25mg of CBD in each capsule for $79 per bottle (30 softgels).

The official Xwerks website advertises a handful of ways in which athletes can benefit from CBD. Xwerks claims CBD can help with recovery by reducing inflammation from exercise and training, for example. It can also help you sleep, relieve anxiety and stress, and promote a general sense of calmness.

Receptra Naturals is a CBD provider that meets extremely high production standards. By offering CBD-only products that contain no THC, Receptra is able to offer their products in 50 US states, as well as meeting the standards of a number of international countries that allow CBD sales.

Receptra offers a range of different CBD products that contain different levels of CBD, as well as providing a comprehensive analysis of each product on the label. Importantly, Receptra also makes third party lab tests on their products available, which allows buyers to make informed decisions regarding their product range.

NanoCraft CBD uses trendy science to differentiate itself from other CBD producers. The company claims to manufacture its products using nanotechnology, which means active ingredients are encapsulated in ‘nanospheres’ or ‘nanoemulsions’, making the ingredients smaller and more bioavailable. All products are lab tested, which is pretty much standard across the CBD industry.

Using this nanotechnology, NanoCraft has created a wide range of CBD products, including softgels, drops, pain sticks, and supplements. All products are available for purchase online and can be shipped across the United States.

NanoCraft is also one of the few companies that makes CBD water. The company’s Craft H20 CBD Recovery Water is so popular that it’s frequently out of stock. The water works as you expect, helping you stay hydrated while also enjoying the effects of CBD. Other unique products from NanoCraft CBD include their pain salve, which comes with 500mg of full spectrum hemp-derived CBD oil in each package. You can apply the salve on aching areas of your body after a hard workout to enjoy relief.

BioCBD+ is another CBD supplier that maintains a presence both in the US an internationally. BioCBD+ has an office in Northern Ireland, and is a top-ranked company due to the high quality range of CBD oil extracts it offers.

The BioCBD+ range contains a unique selection of water-extracted CBD solutions that integrate Ayurveda medicinal practices in an interesting and highly effective fusion of ancient and cutting-edge medicinal arts.

The most popular CBD tincture offered by BioCBD+ is designed for topical use in order to treat joint aches, pains, and arthritic conditions. Instead of offering CBD isolates, BioCBD+ supplies full-spectrum options.

Utah may not be a US state that is closely associated with CBD oil or hemp extraction, but Hemplucid — based in Provo, UT — is one of the best suppliers for hemp extracted CBD tinctures on the market today. The customer reviews for Hemplucid show that the range of CBD products the brand offers is extremely high quality and are effective in treating a wide range of different debilitating health conditions.

Hemplucid also makes independent third party laboratory test results assessing the quality of their CBD products available on the Hemplucid website, and ensures that all products meet the 0.3 percent or less THC content in order to make them complaint with US CBD law.

The extraction process used by Hemplucid is unique — Hemplucid uses the entire plant in the extraction process when creating CBD oil.

Spruce CBD, found online at TakeSpruce.com, offers lab-grade CBD oil tinctures, topical creams, and more at a wide range of potencies. The company’s “Max Potency” full spectrum CBD oil tincture, for example, comes in a 30mL bottle containing 2400mg of CBD at a price of around $270. A smaller bottle of CBD oil tincture is also available, offering 750mg of CBD for $89.

One of the unique things about Spruce CBD is that you can choose the carrier oil you wish to use with your CBD. Hemp seed oil and coconut MCT oil options are both available. In addition to their popular CBD oil, Spruce CBD offers a 300mg topical CBD cream for $39. Spruce CBD claims you can apply the cream as often as needed to the targeted area of your skin to enjoy powerful pain relief. Spruce CBD’s products are organic and made in the United States, although it’s unclear from where in America the company sources its hemp.

Spruce CBD is a brand owned by Spruce Naturals Labs in Raleigh, North Carolina. Spruce Natural Labs is a family-owned business “founded in the belief that modern medicine is broken and in need of alternatives to dangerous pharmaceuticals.” The company’s website is filled with testimonials from customers comparing the pain relief effects of CBD oil to traditional painkillers like oxycodone, with one reviewer claiming the CBD oil “works twice as well” as an oxycodone.

Made By Hemp, found online at MadeByHemp.com, is a CBD retailer and manufacturer featuring a range of products from different manufacturers – including themselves. The Michigan-based retailer claims to individually vet and test each product listed on its online store. During testing, the cannabinoid content of each CBD product is confirmed by a third party lab. If a product doesn’t pass the test, then MadeByHemp.com doesn’t sell it.

Interestingly, Made By Hemp also claims to taste test each product before listing it on its online store. “We use ourselves as guinea pigs,” proudly proclaims the official website, analyzing each blend for flavor, potency, effectiveness, and uniqueness.

In 2016, Made By Hemp opened its own Michigan production facility, where the company continues to produce its own hemp and CBD products. The 1200 square foot production labs is located just outside of Grand Rapids. Today, the Made By Hemp website features capsules, concentrates, edibles, isolates, patches, skincare products, suppositories, tinctures, vape oils, pet products, and more

Dixie Botanicals offers a range of CBD health products that are distributed by Naturewell, a widely-popular natural health product company that is a major supplier for US brands such as Walmart and Amazon.

The Dixie Botanicals product line was one of the first brands to attempt to provide a solution to the controversial taste of CBD, which some consumers find harsh. The Dixie Botanicals line contains stevia, a healthy natural sugar-free sweetener, in order to improve flavor, making the Dixie Botanicals line more palatable than other natural CBD options.

VerifiedCBD is an online CBD retailer and manufacturer that ships to 50+ countries worldwide. The company aims to sell high-quality CBD products at a reasonable price. VerifiedCBD makes its products in an FDA-registered, cGMP-certified facility in Miami, Florida. The company’s website makes it look like a third party middleman; however, all of the products listed on the VerifiedCBD online store are made and sold directly by VerifiedCBD.

VerifiedCBD is best-known for its CBD oil, which, according to the company, undergoes rigorous testing after being produced in Florida from US-sourced hemp. The company claims to test for potency as well as for unique terpene profile, pesticides, heavy metals, and microbiological contamination. The VerifiedCBD CBD oil is available in 750mg (2.5%), 1500mg (5%), and 3500mg (12%) varieties.

Other VerifiedCBD products include full spectrum CBD oil (300mg or 1%), CBD capsules (10mg per capsule, 600mg per bottle), CBD sleep spray, vape oil, dog treats, topical pain rubs, and even a ‘weight loss spray’, among other trendy CBD products. Free shipping is available not only across the United States, but also around the world. Orders are shipped from Miami in 24 hours.

Pure Spectrum offers a range of full-spectrum CBD oils that are sourced from hemp grown in Colorado by the Colorado Cultivators organization. The Pure Spectrum team follows responsible CBD supply procedures, advising customers to perform extensive research and medical consultation before beginning CBD use.

All of the products in the Pure Spectrum range are subjected to independent lab testing, the results of which are published and made available on the Pure Spectrum website. The site also offers a detailed breakdown of the ways in which CBD is able to improve the overall health of the body and mind.

CBD Drip uses CO2 supercritical extraction methods to capture high-potency CBD from EU-certified organic hemp. The terpenes and cannabinoids extracted from the EU hemp used in the CBD Drip product line is created without the use of chemicals and solvents, leaving the vital nutrients highly bioavailable.

The hemp used to create CBD Drip CBD oil is grown in the Netherlands, but the head office is based in Newport Beach, CA.

Founded in 2015, CBD Essence is a veteran of the CBD industry. The company has five years of experience selling medicinal-grade CBD oil tinctures, capsules, and edibles to customers across the United States. CBD Essence is a subsidiary brand of NutraHemp Group, which was founded by a man named Don Ballou. Don spent 30 years fighting ADHD symptoms using conventional techniques and medications. Then, he stumbled upon CBD oil and started “living the full life he dreamed about” free of ADHD symptoms. Other notable brands in the NutraHemp Group family include HempsPets, HempTaffy, and HempChillPill.

CBD Essence’s CBD oil is sourced from 100% organic hemp plants grown in the United States. CBD Essence processes the plants using CO2 extraction, which is the same process used by every other reputable CBD company on the market today. The end result is a full spectrum CBD oil made with natural, organic ingredients and tested by a third party lab using non-GMO ingredients. CBD Essence also claims its products are “micro-aligned to be absorbed under the tongue.

In addition to selling conventional hemp oils, CBD Essence sells a range of CBD hemp tinctures, edibles, capsules, vapes, topicals, and pet care products, among other products. The company is based in the Tampa / St. Petersburg area of Florida, with the hemp sourced from sustainable, organic growers located elsewhere in the United States.

Elixinol is a unique CBD supplier that uses CBD extracted from hemp plants grown in a range of different international locations, all of which provide unique phytocannabinoids and CBD profiles. All of the sources used by Elixinol are subjected to intensive scrutiny in order to ensure they meet a high standard of quality.

Elixinol is notable for the flavored CBD product options they offer, and are one of the few CBD suppliers that provide a certified full product laboratory breakdown of each individual product in their range on the Elixinol website.

Curaleaf is a large CBD retailer that sells a wide range of cannabis brands and products at a chain of retail stores across the United States. Curaleaf is the largest national retail dispensary brand in the United States, offering a range of vape oils and concentrates; flowers, pre-rolls, and flower pods; topical lotions; capsules and tinctures; mints and lozenges; and edibles.

Curaleaf was founded with the belief that cannabis “is powerful and can help improve lives”, according to the official website. The company’s slogan is, “Live Life Well”. All products are organized under three brands, including Curaleaf, Curaleaf Hemp, and UKU Craft Cannabis. Products are available in a range of strains, dosages, flavors, and formats to suit a range of tastes.

As of 2019, Curaleaf cannabis stores can be found in 13 states, including Arizona, California, Connecticut, Florida, Kentucky, Ohio, Maine, Maryland, Massachusetts, Nevada, New Jersey, New York, and Oregon, with retail licensing expected in Pennsylvania in the near future. The company operates about 50 dispensaries in total with more than 1 million square feet of production space and 1,600 employees, although they expect both numbers to double by the end of 2020. Curaleaf is also a publicly traded company (CSE: CURA) (OTC: CURLF).

Savage CBD offers full spectrum, natural CBD products, including tinctures, vape juice, topicals, pens, cartridges, gummies, and softgels. The Irvine, California-based company sells its products online through SavageCBD.com. Products are tested by a third-party, independent lab, with all test results published online. Military discounts and an affiliate program are available.

Free shipping is available for all orders within the United States. Savage CBD also sells CBD wholesale and is open to white label partnership opportunities. Savage CBD is transparent about its address and contact information. However, it’s unclear from where the company sources its hemp.

Of the 25+ products currently sold by Savage CBD, the CBD gummies, full spectrum CBD tincture, full spectrum lotion, and CBD vape juice are the most popular. The company’s lotions and tinctures come in a variety of flavors, including “Lavender Citrus” and “Lemon Lime”, with Savage CBD using essential oils to create the flavors. Multiple strengths are also available for the tincture, including 1,000mg ($100), 1,500mg ($120), and 2,000mg ($150) varieties.

Calm by Wellness is a CBD company founded by a self-described group of “farmers, scientists, researchers, and individuals who believe that everyone deserves to be their best self.” The company website lists five doctors as advisors. Calm by Wellness products are also specifically endorsed by these doctors and other medical professionals, which is why the company claims their hemp CBD oil is “the most recommended hemp CBD oil in the world.”

Today, Calm by Wellness is best known for its hemp CBD oil. The company sells Peppermint CBD Oil, Strawberry CBD Oil, and Sleep CBD Oil. They also offer CBD gummies. The CBD oils are available in strengths from 250mg to 1,000mg, while the gummies each contain 10mg of CBD (there are 30 gummies in each $59 bottle).

Sleep by Wellness also differentiates itself from the competition with its monthly subscription options. You can save 10% by subscribing for a monthly delivery of Sleep by Wellness CBD oil products. All products are made using natural ingredients and broad spectrum hemp extract. The 250mg hemp oil is priced at $50, while the 1,000mg hemp oil is priced at $128.

Ultimately, Calm by Wellness offers competitive prices for its high-quality hemp CBD oil. There are few other CBD companies with the same number of doctor’s recommendations, making Calm by Wellness one of the better CBD companies available today.

Fountain of Health CBD, found online at FoHCBD.com, is a CBD retailer and manufacturer best-known for its CBD oils and topicals. Today, Fountain of Health CBD sells a range of oils and topicals in a variety of strengths and flavors.

The online store features Blood Orange and Tropical Mango CBD oil, for example, as well as unflavored CBD oil. A small bottle (0.5 ounces) is priced at $65 for 1,000mg of CBD, while a large bottle (1 ounce) is priced at $111 for 2,000mg of CBD. The CBD topicals, meanwhile, are available as lip balms ($25 for a 3 pack), skin soothing slaves ($55 to $90), or pain relief salves ($55 to $90). Fountain of Health CBD also sells a “Cool Aid Muscle Roll-On” that makes it easy to apply CBD topicals to your skin on-the-go.

Fountain of Health CBD sources its CBD oil from Colorado-grown, high-CBD hemp with naturally low THC levels (less than 0.3%). The CBD oil is gently extracted with CO2 to ensure no residual solvents are present in the finished product. Fountain of Health claims this leads to “the highest quality available” CBD oil. Full spectrum CBD oils and full spectrum salves are both available.

Mission Farms is based in Bend, Oregon. The company was founded in 2018 by eight Bend locals who failed to find positive results for their medical conditions from conventional pharmaceuticals. They turned to CBD as a natural alternative. Several of the founders had been farming hemp for years, so they naturally decided to launch their own CBD company. Today, Mission Farms pumps out well-rated CBD oils, topicals, and other products.

Mission Farms CBD claims to source its products from “the Napa Valley of hemp”, which evidently lies in the sun-drenched, volcano-rich soil of central Oregon. The hemp is grown organically, which is why Mission Farms says its customers shouldn’t settle for CBD that’s “the equivalent of boxed wine.”

Popular products form Mission Farms CBD include the Rest CBD Oil (for sleep), the Relieve CBD Oil (for pain and discomfort), the Relax CBD Oil (for stress), and the Pure CBD Oil (for general wellbeing). Mission Farms also sells a range of topical creams containing 300mg of CBD, a CBD roll-on product, and a popular Relieve CBD Joint and Muscle Gel in jar or pump bottles. The products claim to get your body back into action. There’s even a CBD goat milk product containing 200mg of CBD.

Lord Jones also offers a popular lineup of CBD chocolates and confections. These products are made in small batches from single origin Ecuadorian dark chocolate, imported European fruit essences, and broad spectrum CBD from the United States. The Lord Jones topical products, meanwhile, have been developed by “a veteran team of personal care experts to deliver broad spectrum relief”, while the tinctures are crafted from five pure and simple ingredients to deliver maximum CBD benefits.

Today, popular Lord Jones products include the company’s High CBD Formula Heavy Duty Chill Balm (200mg of CBD per jar), the High CBD Formula Bath Salts, and the Lord Jones Royal Oil (1000mg per bottle). Lord Jones is also known for its gumdrops, body lotions, tinctures, and chocolate chews, among other products.

Lord Jones was created by the same marketing executive who popularized Larabar, the nutrition bar company. Today, the company is known for its high-potency CBD products delivered in flashy, luxurious packaging. It’s also backed by a surprising number of celebrity endorsements, and Lord Jones seems to get more high-profile press coverage than the average CBD brand. Los Angeles-based celebrity fitness center Equinox, for example, recently partnered with Lord Jones for their “4/20 Workout”.

Pure Relief aims to “usher in a new age of hemp” with a range of CBD and hemp products. Today, popular Pure Relief products include the company’s Relief Rolls and E-Hemp Pens. Pure Relief also sells a range of popular “bundles” ideal for beginners and advanced CBD users alike, including the Spirit Bundle, Daily Dose Bundle, CBD Starter Bundle, and Flower Pack Bundle, among other bundles. Bundles contain different ingredients for different targeted benefits. The Daily Dose Bundle, for example, contains a bottle of Pure Hemp Full Strength CBD Oil, Pure Hemp Relief Cream, and Pure Hemp Gummies.

Pure Relief was founded by Michael Melton, who previously owned a tire store. Melton believed good CBD products could help relieve the opioid epidemic in his home state of North Carolina. The company sources its hemp from Colorado, using CO2 extraction methods to ensure only pure CBD with no additives or solvents in the final product. Pure Relief also claims to have a team of pharmacists, stating that all company products are “formulated by experienced pharmacists with decades experience”.

All Pure Relief products are lab tested for purity and quality. Lab results are viewable online at the official Pure Relief website. You can buy a wide range of CBD flowers, oils, relief rolls, “Palmwoods”, bundles, vape pens, gummies, topical creams, and other products online today through the company’s online store.

Balance CBD is a natural wellness company specializing in CBD. The company was founded by Carolina Thien and Dr. Manpreet Bajwa in 2017. The two launched the company after meeting while attending a health conference in Vancouver, Canada. Today, Balance CBD offers a range of CBD products that are made in the United States, THC-free, organic, vegan, cruelty-free, and allergen-free. Balance CCBD is owned by a San Francisco-based company called AAXLL Supply Co LLC.

All products are also third party lab tested at multiple stages of processing. Balance CBD tests its seeds, for example; the company tests its hemp plants while they are growing in the fields; and the company tests its CBD extracts through each stage of the purification process. “Only by doing this can we guarantee our products are pure and safe,” explains the official website.

Today, Balance CBD is well-known for popular products like the Charlotte’s Web THC Free CBD Oil Tincture, available in strengths of 500mg and 1,000mg. The oil promises to provide a significant dose of high quality CBD with natural terpenes. Other popular Balance CBD products include the CBD gummies Mixed Variety Pack and the Disposable CBD Charlotte’s Web Vape Pen. Balance CBD offers its popular CBD gummies in multiple flavors, including raspberry and “Orange Dreamsicle”. Balance CBD also sells CBD JUUL Pods, CBD suppositories, CBD products for pets, and other unique CBD products.

Feals is a CBD startup launched in 2019 by three ad-tech veterans. The trio launched Feal with the goal of making CBD as accessible as possible. Today, Feals sells CBD products as a one-time purchase or as a subscription. However you buy their products, Feals will deliver high-quality CBD direct to your doorstep.

You can order a $20 ‘flight’ from Feals, letting you try out three different strengths of CBD tinctures. Then, once you know which strength you like, you can buy the Feals tincture that works for you. There are 600mg ($75), 1200mg ($135), and 2400mg ($245) options available with doses of 10, 20, or 30mg, respectively.

Feals sources its hemp from family hemp farms in Colorado and Oregon. As with other CBD companies, the hemp contains less than 0.3% THC. Feals also emphasizes a whole plant approach, which means CBD isn’t the only cannabinoid in the finished product. Other naturally-occurring terpenes will be found in the final product as well. Feals also uses MCT oil as a carrier in its formula, although MCT oil and hemp oil are the only two ingredients in the tincture. MCT oil, of course, is its own trendy ingredient: the coconut-derived oil is used to burn fat, boost metabolism, and enhance brain activity, among other purported benefits.

Isodiol International, LLC is one of the leading CBD product retailers on the market today. Founded in 2014, the publicly-traded company (ISOLF) sells a range of its own Isodiol branded products while also distributing bulk CBD formula and white label CBD products to third parties. Other subsidiaries under the Isodiol International brand include Biosynthesis Pharma Group and Farmtiva, LLC. Isodiol continues to acquire smaller companies regularly, and the Isodiol family continues to grow.

Isodiol makes CBD products using non-GMO hemp, with each batch third-party tested and guaranteed to be free of pesticides and heavy metals. The end result is that all Isodiol products are made with 99% or higher pure, natural CBD and guaranteed to be THC-free.

Today, Isodiol’s top-selling products include a natural hemp oil tincture called RapidCBD Pure, a cooling CBD pain cream called Iso-Sport Mend, and a cannabinoid-rich coffee product called Pot-O-Coffee Jamaican Me Crazy. Isodiol also offers bulk CBD and white label CBD formulas for companies wanting to market their own CBD products. Overall, Isodiol offers a wide range of CBD additives, beverages, candies, capsules, coffees, oral sprays, tinctures, topicals, and vapes under its own brand, subsidiary brands, or through white label partners

Ananda Hemp is one of the few non-US based CBD providers in this guide, and is owned by an Australia-based parent company called Ecofibre. The Ananda Hemp head office is based in Manchester in the UK, and sources CBD extracts from hemp grown on a privately-owned US-based farm in Kentucky.

The most popular products offered by Ananda Hemp are the Spectrum 200 and Spectrum 600 CBD oils, both of which are full-spectrum solutions that contain organic cold-pressed hemp seed oil. Ananda Hemp also uses flower extract in their solutions, which function as a herbal remedy that can be used to improve a wide range of health conditions.

Founded in 2017, JustCBD is a Florida-based CBD product maker offering a range of CBD products available to be shipped across the United States. Today, JustCBD is best-known for its CBD gummies, full spectrum tinctures, and CBD protein bars, among other products. The company also makes unique products like bath bombs, CBD products for pets, and even CBD dried fruit.

We particularly appreciate the variety of sizes and pricing options available with JustCBD. The company offers its popular full spectrum tincture in sizes ranging from 50mg to 1500mg, for example (priced from $18 to $140). A surprising number of other CBD companies only sell one or two sizes.

The CBD gummies are sold in an equally impressive range of sizes ranging from 250mg ($24) to 1000mg ($60). Two classic flavors are available, including ‘Clear Worm’ and ‘Sour Worm’. Want to enjoy the effects of a CBD gummy without sugar? JustCBD also offers a sugar-free CBD gummy. ‘Jet Setter’ CBD multivitamins, CBD protein bars, CBD vape oil, and CBD isolate round out the unique selection of CBD products available from JustCBD.

Herbal Renewals is a popular brand that is oriented toward the creation of full-spectrum extract CBD oils and products. The Herbal Renewals tincture range varies in potency, beginning with 150mg of CBD in the Blue Label and Green Label products up to 240mg of CBD in the Gold label range.

Herbal Renewals does provide a high level of CBD in their product line, but lacks the transparency in the manufacturing process offered by other higher ranked companies. The selection of products offered by Herbal Renewals is extensive, however, which makes up for their lack of transparency, and they are backed up by positive customer reviews

Like many other CBD companies, Royal CBD uses a CO2 extraction system to withdraw the active compounds from hemp plants. Unlike certain other CBD companies, however, Royal CBD uses full spectrum CBD extracts sourced from fully organic hemp. There are no pesticides and no GMO ingredients, and all products are tested in independent labs for potency and purity. Royal CBD combines the hemp oil with cold-pressed premium-grade MCT oil.

Royal CBD is based in Anaheim, although the company doesn’t disclose the source of its hemp and CBD. Royal CBD does claim to get its hemp from domestic suppliers, although it’s not clear where that hemp is grown. Royal CBD’s most popular product is its Full Spectrum CBD Oil. The CBD oil is available in 250mg ($50), 500mg ($75), or 1,000mg ($130) sizes. Royal CBD also sells CBD softgel capsules for $85 for a 30 pack with 25mg of CBD in each capsule.

Overall, Royal CBD seems to be a high-quality domestic supplier of CBD and CBD products, although we would appreciate further transparency regarding where the hemp is sourced. Founded in 2019, Royal CBD is also one of the newest members of the CBD space.

Mana Artisan Botanicals is one of the only CBD manufacturers based in Hawaii that uses Hawaiian-grown hemp in the production of their CBD line. The Mana Artisan Botanicals brand closely follows the traditional healing practices of Hawaiian culture, focusing on a respect for people and healing compounds.

The Mana Artisan Botanicals CBD oil selection is created with a foundation of sustainable and minimal environmental impact — the co-founders of the brand are directly connected to the Wholistic Research and Education effort that funds medical cannabis investigations in partnerships with major universities around the world.

Mana Artisan Botanicals products include massage and topical oils, and have been tested in accredited labs for potency, and quality, with testing results available on request.

Sunsoil makes full spectrum CBD oil from organically farmed ingredients. The company grows its products at a farm in Vermont, and all company products are USDA Organic certified. As explained by the official company website, Sunsoil emphasizes “transparency and quality at every step from seed to shelf.”

Today, Sunsoil sells a small selection of CBD oils and CBD capsules, including Sunsoil CBD Oil (available in Unflavored, Chocolate Mint, and Cinnamon), Sunsoil CBD Oil Softgels (20mg of CBD per softgel), and Sunsoil CBD Coconut Oil (600mg total CBD per jar). The CBD oils contain 600mg of CBD in each 60mL container, while the softgel capsules are available in 600mg or 1800mg packages (both of which have 20mg per capsule).

Sunsoil also differentiates itself from the competition by processing CBD oil naturally using only coconut oil in a process known as lipid extraction. That oil is sent to a third party lab to be tested. After adjusting the concentration, Sunsoil sends the oil back to get tested again. Once the quality and concentration are confirmed, Sunsoil fills its packages to an exact volume using “pharmaceutical grade robots and equipment”. In other words, you’re getting the best combination of technology and high-quality organic growing.

Some of the very best hemp in the world for CBD applications is grown in Colorado. Pure Hemp Botanicals, based in CO, uses Colorado-grown hemp in the creation of their CBD products. Working in partnership with a number of different high-profile Colorado-based CBD companies, Pure Hemp Botanicals cooperates with Advanced Plant Processing and Greenhouse Growing System to deliver high-quality CBD products.

Customer reviews for Pure Hemp Botanicals indicate that the brand’s products are highly effective in treating anxiety, PTSD, stress, anxiety, sleep disorders, migraines, and glaucoma. Pure Hemp Botanicals makes extensive lab testing of their products available on the brand website, and lists the batch number of each CBD extract on their product labels.

Pure Hemp Botanicals also donate 1% of the proceeds from the sale of each product to Mercy for Animals, a non-profit anti-animal cruelty charity.

4 Corners Cannabis is a privately-owned CBD product supplier that boasts over 30 years of cannabis growing experience in the founders team. Based in Colorado, 4 Corners Cannabis retains total control over the growing process of the plants that are used to create their CBD extracts, and is typically working with more than 100 CBD-rich strains at any given time.

The most popular products offered by 4 Corners Cannabis are tinctures that, according to customer reviews, are highly effective in treating chronic pain as well as the symptoms of anxiety disorders. Interestingly, 4 Corners Cannabis CBD extract uses only CBD dominant hemp strains, as well as an orange oil in order to deliver a rich citrus flavor.

Green Garden Gold is a highly reputable CBD product supplier that draws from a variety of certified high quality hemp sources grown in the northern hemisphere, primarily Europe. The core goal of the Green Garden Gold team is to sell CBD products that can be used to treat a variety of chronic health conditions.

The hemp used in the Green Garden Gold range of products is hand-picked in Europe, and is an internationally recognized hemp supplier. The Green Garden Gold range contains creams, oils, and supplements. The most popular product sold by Green Garden Gold, the Med Pac CBD Oil, uses rigid CO2 extraction technology to provide full-spectrum CBD benefits

Ambary Gardens is an extremely unique CBD company. Unlike other CBD providers, who typically purchase raw hemp from growers, Ambary Gardens controls every single step of the growing, extraction, and manufacturing process.

This allows the Evergreen CO based company to grow their own hemp in advanced sustainable greenhouses and incorporate quality control at every step of production. The third party testing that backs up Ambary Gardens is performed by the highly reputable Botanacor Labs testing authority.

Ambary Gardens offers CBD suspended in MCT coconut oil, which delivers a longer shelf life and a range of additional health benefits.

IrieCBD was founded in 2014 in San Diego. Today, the company continues to sell CBD products that spread “San Diego beach culture” and “California’s zest for life” across the country, according to the official website.

The company also emphasizes healing more than most other CBD brands. Many of the company’s products are designed specifically for health and wellness. They claim to soothe pain at the source, for example, while delivering a “full spectrum of benefits”. IrieCBD also grows its non-GMO hemp on sustainable, pesticide-free farms. Plus, all IrieCBD extracts are made from pure, raw, whole plant hemp material to create full spectrum hemp oil. All products are also tested in independent, US-based labs.

IrieCBD’s most popular products include CBD Oil Pain Cream with Celadrin, “Pain” 250mg CBD Oil Tincture, and a “Calm” 250mg CBD Oil Tincture. Other products in the IrieCBD lineup come with marketable names like “Daily”, “Balance”, “Relief”, “Lifeline”, and “Feminine”. IrieCBD even makes a “Pet” CBD Oil Tincture. All tinctures, according to IrieCBD, are formulated by herbal and nutritional experts to “deliver targeted relief and supportive effects on the body’s natural systems”. The tinctures are priced between $30 and $40 for a 32mL bottle containing 250mg of CBD. In recent months, IrieCBD has also launched a lineup of face serums under the IrieCBD Skincare brand.

Based in Michigan, Tasty Hemp Oil focuses on making palatable CBD oil products that are available in a wide range of flavors. While Tasty Hemp Oil doesn’t offer groundbreaking extraction methods, the range of flavors they offer and the quality of their product line makes them the final addition to our list of the top 40 CBD oil suppliers online.

Entourage Hemp, based in Denver, CO, specializes in the manufacture and distribution of a wide range of natural hemp products. The Entourage Hemp line allows consumers to choose from three different delivery methods.

Entourage Hemp sells naturally flavored CBD e-liquids for vaping, soft-gel capsules that contain organic ingredients, and a range of sublingual tinctures that contain high purity CBD. Interestingly, Entourage Hemp was one of the first CBD companies to offer enhanced potency oils to the consume market.

The manufacturing process used by Entourage Hemp follows the WholeFlower principle, which results in the creation of full-spectrum CBD extracts by using only hemp flowers in the extraction process. The entire Entourage Hemp range is backed up by third-party accredited laboratory tests that prove the purity and quality of their CBD line.

What a list of reputable CBD-focused brands! The largest, most popular CBD companies above were weighted by many other social stats and streams such as: Google Search Trends, Alexa, Ahrefs, SEMRush, SimiliarWeb and over 30 Top CBD Oil Review publication's aggregate rankings.

One consideration to note is this catalog of companies is ever-evolving and will continue to receive changes as more data is compiled and collected. Here is the entire list of companies we are looking to review and add to the top ratings should qualitative metrics move up and justify inclusion in the specialized ranking system.

Be sure to revisit this list of honorable mentions who are under investigation by the TimesofCBD research team to be added into the ratings.

Now that we have uncovered the 30 best CBD products while unearthing the top 70 cannabidiol-branded companies, let's unify what CBD is and go through part two; an all-encompassing frequently asked questions FAQ section, a buyer's guide mixed tons of accessible scientific-literature.

Now that the top 50 cbd oil companies rankings from the best-brands in the world are revealed, let's piggy back on the opening introduction and give a proper, necessary ‘what is CBD' guide.

As alluded to, dissecting the industry's bright outlook and all the various types of CBD product forms – to how we rated the top products and ranked the best companies, let's get into the ‘science' of the supplemental ingredient that has surpassed all other extracts in terms of sales, use and popularity in the United States.

Between the video above and the visuals to follow, along with a detailed question and answer section, it will be the perfect segway into all of the scientific data towards each and every medical condition CBD has been known to help. Due to CBD's Schedule I drug classification it has severely limited the amount of studies researchers can do on the compound, but here is what is currently being circulated and verifiable.

Yes, hemp oil and hemp-derived CBD products have came a long way since 1937 marijuana prohibition days to 2014, 2018 until 2019. Hemp, has been known to be made into at least 25,000 different products (US Congress study) – from food to clothing to cosmetics to fibers to paper to textiles to fuel – it can do everything wood can do at a renewable rate and now, arguably its most sought after quality and characteristic – CBD – is ready for the mainstream spotlight and this guide was meant to help eliminate the level of guesswork involved.

We know the popularity of CBD is in large part to its beneficial health effects but also can be attributed to its versatile, adaptive properties and functional mechanisms by binding with the human endocannabinoid system. Here is a visual breakdown of what the medical world has discovered to date.

The uncanny natural neurotransmitter receptor (CB1 and CB2) compatibility and uplifting effects on the body's endocannabinoid system (ECS) embodies a profound paradigm. In what are vastly uncharted health horizons coming of age, a Labroots executive painted the picture:

“In the pursuit of unearthing the metabolic pathways of phytocannabinoids and endocannabinoids, scientists came across and unknown molecular signaling systems within the body that is involved in regulating a broad range of biological functions. This system was named the endocannabinoid system (ECS).”

As a result, once it’s taken, CBD possesses the property of going to wherever it is needed the most in the body. This is why some people have started referring to it as a “miracle” marijuana molecule. This is obvious due to its versatile nature of operations within the body's internal ecosystem.

It’s been known to provide relief for everything from mild joint pain to acute conditions like irritable bowel syndrome, and Crohn’s disease, to severe life threatening conditions like epilepsy and seizures. We will elaborate extensively on this below where you can sift through a table and mountain of data supporting each individual case.

In fact, compared to all other single-spoken ingredients, while it sounds as bold as it gets, it appears that there’s no end in sight to what it can do to improve human health and provide relief where necessary. As more research and studies are carried out, we’ll see the extent to which it can help humanity become even healthier and stop relying on so many harsh side effects many of the current solutions provide.

While it’s not a cure-all and nothing is guaranteed–at least not yet- it is helping out with enough health conditions to warrant the popularity it’s obtaining.

Before we get into where to buy CBD oil (see below), let’s go over the three main types of CBD concentrates.

The lack of regulations regarding the sale of CBD products presents a lot of problems. One of the biggest concerns is the way CBD is extracted.

There are a few ways to get CBD from the hemp plant. One of the safest ways is to use carbon dioxide (CO2). The catch is that CO2 extraction uses expensive equipment that can take a while to learn to use efficiently.

CO2 extraction is the most preferred method of extraction because the resulting product is as close to being pure CBD as possible.

Ethanol is a cheap alternative to the expensive CO2 method. However, ethanol breaks down other compounds the hemp plant contains that many patients prefer to be left behind in their supplements.

Any kind of fat or oil can be used to extract CBD. Green Mountain uses coconut oil, but everything from olive oil to butter can and is used.

Oils are a cost-effective natural solution for CBD extraction but the downside is they are perishable. CO2 and ethanol extracted CBD can last indefinitely. More on this down below.

Marijuana and hemp plants both produce many other compounds, not just THC and CBD. The combined effect these different chemical compounds have on the body is the entourage effect.

Myrcene, for example, reduces the resistance of the blood-brain barrier to cannabinoids. This effect helps the body to absorb the more beneficial compounds, like CBD.

Cannabis plants can be grown to accentuate certain compounds. The strain of hemp known as Charlotte’s Web has a high CBD content and low enough THC level that it can be sold in every state.

So CBD capsules from two different brands with different suppliers can result in totally different chemical makeups.

One of the most distinctive CBD terms floating around the industry are the three most common ways CBD products are marketed.

While the promotional side of these styles of CBD oils want to claim the inclusion of diverse compounds that encompass the entourage effect, it is time to stop and wonder the differences between these three cannabinoid spectrum identities. In an attempt to make sense of it all, the one stickler most endure when selecting the right CBD is the fear of THC quantities in each oil. Let's see how each of these unique product characteristics contribute are beneficial to the body's health yet offer very different qualities.

The most basic way to define CBD isolate is to refer as it only ‘housing' cannabidiol, that is, every other known terpene, flavonoid and cannabinoid compound (over 100) has been removed.

It is referred to as ‘pure cannabidiol extract' and is usually extract by either an ethanol solution or supercritical carbon dioxide (CO2) method. Once it is followed up with a chemical wash, it's final form is a white powder and is best-associated with its versatility despite the entourage effect no longer being in play.

Due to its pureness (i.e. homogenous solution), it has suggested uses for being easily infused into different types of products, hence the reason why the market currently offers topicals, capsules and edibles etc. Another feature that makes isolates preferable is one’s ability to quantify doses taken. As previously mentioned, consumers who wish to play it safe in time for drug tests (especially if their careers are on the line) may prefer to stick to CBD isolates as well knowing there is absolutely no THC in a CBD isolate.

The difference between CBD isolate and full-spectrum CBD rests in the fact that the latter houses traces of several cannabinoids (including THC) versus only containing cannabidiol. Meaning full-spectrum CBD is the option to go with if you want to include all of the varying naturally-occuring plant compounds (i.e. other cannabinoids, terpenes, flavonoids and essential oils). This true entourage effect is thought that all elements together magnify and amplify the therapeutic benefits of each other.

Initially, consumers were informed that CBD isolate in its truest form is as effective as it could get, but as per a 2005 study by Lautenberg Center for General Tumor Immunology, it was found that “Cannabis clone 202 (Avidekel) extract is superior over CBD for the treatment of inflammatory conditions.” This evidently led to more studies combining cannabinoids.

And back to the start – due to the afraidness of unknowingly consuming THC for a variety of reasons, there is a specific type that alludes to that very fact that no THC is in the product. It is essentially a hybrid between a full-spectrum CBD and pure cannabidiol isolate. It will host all of the whole-plant cannabinoids, terpenes and flavonoids but with the exception of zero THC. However, the THC-free broad-spectrum distillate is the newest look of CBD oil products compared to the former polarities of the others and requires more studies.

For the moment, it is too soon to tell as the number of studies that currently exist within the industry is quite minimal. While it is true that many studies have found CBD as being effective because of its anti-inflammatory properties, and others supporting the CBD and THC pairing, most often, the sample sizes aren’t large enough, the studies lack replication or the source of cannabis used may or may not be potent enough (depending on existing laws).

That said, consumers have to decide based on their needs and beliefs. For instance, if one chooses to play it safe, depending on factors like drug tests, the legalization of cannabis in their state or country and fear of the THC experience, it would be ideal to stick to CBD.

If we are talking about an advanced user who is fine with a certain CBD to THC ratio within their products and would prefer to experience the so-called, “entourage effect,” the full-spectrum solution would be the way to go.

Given that broad is, in most ways, like full-spectrum (without the THC of course), then therapeutically, it may be preferred. This is not to say that CBD does not bring results, but rather leads to the question of how soon can they be attainable?

Bearing all this in mind, consumers also need to pay closer attention to their current health conditions and medications intake. This area is also lacking studies, therefore, consumers should seek professional help prior to taking cannabis-related supplements.

Very safe. It’s a non-psychoactive compound, even if it’s from cannabis. Of course, this wasn’t always the case, seeing as its parent plant –cannabis- was largely associated with mental problems, cognitive impairment, and in some cases, death.

Cannabis has gotten such a bad rap that it’ll take a while before that stigma wears off. The thing most people didn’t know is the psychoactive effects were largely from the THC in the plant; not CBD.

CBD doesn’t make you high. It’s provides all the great benefits of cannabis without any of the side effects. So, depending on the right dosages, it will do everything from get rid of your anxiety to control epileptic seizures.

More importantly, it appears you cannot overdose on CBD. This is because, unlike THC that overstimulates your endocannabinoid system, it doesn’t at all. It works in a manner similar to slow release drugs, stretching out its effects for as long as possible.

But as with all things, take it in moderation –better if you stick to the dosages recommended for your conditions.

The most amazing thing about CBD is its dynamism when it comes to the treatment of various health conditions. Conventional medicine routinely administers just one drug for the treatment of one condition.

While this has been efficient, the problem is that treatment can be quite expensive if one has to treat multiple ailments. CBD on the other hand, has proven to be an incredibly powerful adaptogen capable of treating multiple health conditions.

This happens because of it is ability to bind to the body’s endocannabinoid system, thus ensuring that its effects are felt wherever it’s needed. So, whether you have migraines, joint pains, sciatica, seizures or want to increase your focus, the compound takes on all these and provides the necessary aid and relief wherever necessary.

Its effects can also be highly targeted, and capable of reversing the bod’s purported/expected response. For instance, inflammation is usually the body’s response to injury or abnormality.

Unfortunately, this inflammation results in pain –which can be healthy. But when the body has to go through pain/inflammation that’s completely unnecessary, it can be quite uncomfortable. Using CBD to curb these unnecessary inflammation can help provide the necessary relief that you need.

Also, CBD may play a role in slowing down the progression of neurodegenerative disorders like dementia, Parkinson’s and Alzheimer’s. They purportedly do this through their neuroprotective properties, which helps slow down the rate at which neurons and the brain break down or die because of age.

For the most part, CBD has very few side effects and is well tolerated at high doses by the body's system. But it is important to discuss them so they are not unexpected when they do occur.

Tiredness, diarrhea, and changes in appetite are the most common side effects. However, recent studies show that liver organ damage and injury is a rising problem due to poorly-made products which is the main emphasis of how we rated products and ranked companies.

The population that should be most cautious about using any supplement, are pregnant women. The research on how cannabinoids interact with a developing fetus is sparse with inconclusive results.

The one organ that does seem to have a negative response to CBD supplements is the liver. This effect can be magnified if you are taking a medication that is broken down by enzyme CYP3A4.

Enzyme CYP3A4 is responsible for the absorption of over 60% of pharmaceuticals. It is also responsible for the absorption of CBD, which can block other drugs from being metabolized into the bloodstream.

The interaction is not the same for every medication. Consult your doctor because the interaction between your meds and CBD may be negligible.

And CBD’s relationship with your liver may not be all bad. CBD increases your body’s supply of enzyme CYP1A1, known for breaking down carcinogenic compounds like benzopyrene.

The process of taking CBD and enjoying its many benefits is pretty straightforward. It is estimated CBD's full effects last approximately 4-12 hours but will depend on body fat percentage and dosage amounts.

You can just smoke specific CBD rich strains, vape, use the oil or tinctures by placing drops under your tongue and holding it there for as long as possible, swallow CBD capsules, eat CBD infused edibles, and rub CBD ointments and salves on your skin.

These are the best ways to get and use CBD for maximum results. It all depends on your preference or mood at the time. For instance, some people can’t stand the earthy flavor of CBD oil, so they prefer either smoking, eating CBD edibles or applying CBD ointments to their skin.

CBD’s groundbreaking properties are still being studied for its many uses. Who knows if it’ll be the new “miracle” compound that will usher in a new era of health for mankind? Till then though, be smart about using it, and only adhere to the recommended doses. CBD’s many benefits can help you live a richer, fuller and healthier life. Soo, use it when and if it’s necessary.

While most believe they can use these terms interchangeably, they are technically not the same product. While both may look the same and stored in similar bottles, it boils down to the actual processing used in cultivation. The main distinguishment between a CBD oil and CBD tincture is how each is of the cannabis plant's constituents are extracted. In the most basic explanation, a tincture is created by soaking the cannabis plant in a water and alcohol solution, where as a CBD oil must be infused in a carrier substance, usually hemp seed, olive oil or coconut oil.

Easily one of the most frequently asked questions and the main reason why it was covered in the introduction is CBD does not contain THC, which is the psychoactive element found within the cannabis plant that is associated with recreational use. The lack of THC makes CBD non-psychoactive. CBD works by interacting with the endocannabinoid system and does not cause any unwanted ‘high' side effects. Be sure to read the health benefits section below as well as sifting through all of the medical documentation listed. The most popular beneficial wellness effects of CBD include:

Unlike THC, which produces near immediate feelings when smoking it, CBD has a bit more subtle approach given it does not make you high. While enhancing the CBD effectiveness regarding how quickly it can be felt, it will vary from one person to another. It can depend on the product's potency and bioavailability, or factors like age, metabolism and tolerance. All of these can play a role in how fast CBD gets absorbed into your bloodstream. Recent studies have shown fatty foods can increase absorption due to binding with CBD oil's cannabinoids which help the liver metabolize the compounds quickly when opting for the oral route. Make sure the CBD oil is water-soluble. Other ways to ensure CBD acts rapidly within the body is to inhale/smoke cbd flower buds or take it sublingually under the tongue.

While there is no one dosing time fits all, each routine will largely depend upon the daily symptom, disorder or condition being addressed. A simple example is insomnia users should take it before bed to help with sleep whereas ones trying it for anxiety stress relief should use it in a timely manner an hour or so before a big nerve-wrecking event to help calm nerves. For those in chronic pain or discomfort, taking it when and where needed is likely the best option to follow. Given the level of relaxation or even energized effect desired, no set schedule or strict serving size will work for everyone and is advised to always consult with a healthcare provider first.

As you can see, there are quite a wide variation of CBD brands and their respective product lines to choose from. With so many different CBD products on the market, it can be difficult to determine which substances are of sufficient quality to provide users with the benefits that they are striving for.

One of the best ways to differentiate between high and low-quality products is to opt for formulas that are made with processing methods that users can count on. There are various extraction methods, including CO2 extraction, stream distillation, and hydrocarbon solvents. Here is a bit about each method so that users know what to expect when they purchase products:

There are three types of CO2 extraction methods: supercritical, subcritical, and midcritical. The most commonly used, and the one addressed herein, is supercritical extraction. It is the most common option because it tends to be the safest and it results in a pure product.

According to Marijuana Break, CO2 extraction essentially entails using pressurized carbon dioxide (CO2) to remove CBD and other phytochemicals from the plant. The CO2 essentially functions like a solvent when certain temperatures and pressures are reached.

The main downside of CO2 extraction for many companies is that it tends to require expensive equipment. On the upside, the CO2 extraction process does not damage the product and maintains its quality so that the end result can be safely consumed.

Steam distillation, also known as vapor distillation, tends to lead to ultra-pure and terpene-rich formulas. According to the CBD Awareness Project, steam distillation is a process where steam separates the CBD oil from the hemp plant. The hemp plant is contained in a glass flask that features an inlet and outlet. The inlet is connected to a glass container with water that boils, while the outlet connects to a condenser tube.

The water heats up, and the steam causes the oil to separate from the plant. The liquid is then condensed in a tube, and when collected, the oil and water mixture are separated. The downside of this method that those who apply it must be careful, as steam that becomes too hot can damage the extract and cannabinoids. The benefit is that it could lead to a pure substance.

Hydrocarbon solvents is similar to steam distillation in that it separates the CBD oil from the plant. According to Maximum Yield, it is a popular extraction methods that removes the cannabinoids, such as tetrahydrocannabinol (THC) and terpenes from the plant. The types of hydrocarbons used here include propane and butane.

Precision Extraction identifies several benefits to hydrocarbon extraction. These benefits include versatility, yield, efficiency, safety, and preservation. There are also minimal to no risks involved with hydrocarbon extraction equipment.

Aside from the type of distillation method used, there are a number of other factors that users may want to consider when choosing CBD products. For example, users may want to look for:

These qualities can help users protect themselves by ensuring that the quality of the product is up to par and contains a sufficient amount of CBD.

Now that the main methods used to extract hemp-based CBD are covered, it is best to know that there are many different preserving efforts users can practice to maximize the benefits CBD products have to offer. First and foremost, users should always follow the storage instructions on the packaging. Often, brands know what works well for their products and is the a main component for rating products and ranking companies.

In the event that one’s products do not identify optimal storage methods, there are a number of tactics to consider just like any drugs or other consumables.

The shelf life of CBD oil varies drastically, but in general, the average is anywhere from 14 to 25 months, depending upon how one stores it. How CBD oil products can be degraded will vary as well, therefore users should check the label for information. Simple details like production date, expiration date and quality of hemp used matter. This will give users a good timeframe of how long the oil and/or tincture will last.

Aside from the shelf life, where the label does not share a storage method, users may want to consider refrigerating the product. Generally CBD products do not need to be refrigerated. Instead, most brands recommend that the products be stored in cool and dark place. The cool temperature and the lack of light prevents the growth of bacteria. In the event that users do want to refrigerate their formulas, they may be able to extend the life of unopened CBD products by doing so.

Once receiving the bottle of CBD oil, the first thing to do is check the expiration date just to ensure the product is fresh. Most CBD oils have a 1-2 year expiry date but double checking is always a good idea. While the taste will likely deteriorate once an older product's shelf life gets after being opened, it can also house harmful microorganisms so be mindful once started using a tincture.

The best place would be your medicine cabinet. The reason is simple: if the temperature in the cabinet works for your drugs, you can be sure that it will work for your CBD oil. Avoid keeping them close to heat sources such as microwaves, ovens, and stoves.

Even better, avoid the kitchen entirely. Some people recommend the pantry. Doesn’t make sense to store them there unless you’re buying in bulk. And even then, you have to make sure that the pantry is either somewhat far from the kitchen or consistently cool.

And if you’ll be carrying it around in the car, keep it in the glove box while the AC is on. And when you’re leaving the car, put it in your bag. The only condition in which you can leave it in the car is if the weather is cold and dry.

This is important because heat tends to breakdown the compounds faster, causing it to lose its potency and strength. And once it loses those, it’s no use to you.

Prolonged exposure to light can also break down the molecules. Which is why most recommend keeping it dim or dark places. If it's left out in a bright area, remove it as soon as possible and let it settle back to normal.

Light can breakdown the cannabinoid compounds in CBD oil and alter its taste. Thankfully, most vendors know this, so they sell them in amber or dark green colored bottles.

As with all medicines, unnecessary exposure to air affects its potency. So, keep the cap screwed after use every time to avoid this. And if transferring or consolidating the oil to another container, make sure it’s an airtight one too.

Because it’s oil, avoid storing it in cold places like a refrigerator or freezer. Doing this will cause the oil to congeal, which will in turn, make its dispensing more difficult.

Unfortunately, when this happens, don't be tempted to place it close to a heat source so it can melt before use. This will destroy its potency and effectiveness. Much like the light and heat, leave it out to thaw even if it takes awhile.

Before 2014, cannabis, the parent plant of CBD was largely outlawed in many states. However, California legalized it somewhat in the late 90s, making it available only via medical prescription.

Therefore, while you couldn’t get it anywhere else in the US, you could get in California, IF you had a doctor’s prescription. Of course, this didn’t stop people from still selling it illegally.

Thankfully, cannabis and its many products are legal in most states and Canada. States that haven’t legalized cannabis are currently working on the process of legalization, and drafting the necessary rules.

This means that CBD is largely legal in the US and Canada. You might just have to check with your state though, to see what their laws are, as some aren’t still open to the idea of legalized marijuana.

In Canada however, Cannabis became legalized in 2018. So, wherever you are in the country, you can openly buy your weed and its many products from recognized dispensaries.

You can get CBD in various forms as we covered earlier with oils, capsules, tinctures, edibles, and topical ointments being the most common forms. All of these are available from your local retail stores, dispensaries or online outlets. Just make sure to do your due diligence and ensure you’re buying the real thing. While CBD and medical marijuana are in two different leagues when it comes to legalization, here is a chart representing the growth of medicinal cannabis in US States.

Each individual US State has specific CBD laws and regulations. Look up every CBD state law here; Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington DC, West Virginia, Wisconsin and Wyoming.

If you’re investigating the potential health benefits of CBD, it’s a good idea to take a look at the most comprehensive CBD health benefits guide. There is a vast amount of information available that will assist individuals new to navigating the world of CBD in determining dosing, sources, the different types of cannabinoids, and the best delivery methods.

Before getting started with using CBD to improve your health, it’s always best to consult with your doctor or a medical professional.

Now, let's get into the pure health side of the show and start unfolding all of the main reasons why CBD is the king-kong supplement ingredient of 2020 and beyond.

Cannabidiol owes all of its publicity because of one caveat over them all, its effectiveness. Yes, this compound does come from the very same cannabis sativa plant that is the main source of Tetrahydrocannabinol or THC, but one should never confuse CBD with THC. In general, CBD provides a wide range of beneficial effects while THC is best known for its psychoactive properties of ‘getting high'.

There is a growing number of scholarly articles about CBD and we referenced 123 specific ones for each of the associated claims below. While cannabidiol requires careful consideration of its legal status where you live, it is also important to have a clear idea of what kind of health benefits many expect from CBD.

A more thorough analysis of current literature shows that CBD is a complex concept. For instance, one has to realize that there are differences in the benefits which can be derived from a full-spectrum, broad-spectrum and CBD isolates. Other factors of critical importance include the variety of CBD-extracted cannabinoids and the benefits of terpenes.

But an important reminder to note from Cecilia Hillard, one of the USA's more prominent CBD researchers and Neuroscience Research Center of the Medical College of Wisconsin director:

“We don't have a lot of experience with people taking these drugs for many, many years, and you never know if there could be chronic effects that could pop up” […] “Even at high doses, the effects of CBD itself tend to be mild” […] “But what we know in humans is much more limited,” […] “In fact, there have been only a couple of really good clinical trials done in humans.” […]

And a reiteration of why buying a CBD oil infused product from a trusted brand is so important, the Professor of Pharmacology put it:

“Even in a very careful grow operation it’s easy for hemp and cannabis plants for example to get contaminated with mold. Also depending on how it’s grown, (growers) may be using pesticides.” […] “There’s no regulatory agency that’s overlooking (CBD oil’s) purity, its concentration, whether or not there are other things that are present in the oils like pesticides, or molds, or heavy metals and so forth.”

This in-depth resource will help you gain a much better understanding of why CBD is therapeutic and how it applies its medicinal benefits to each health condition.

One of the most common health conditions that affect the adult population is acne. In fact, at least 54 percent of all adults suffer from it at any point in their lives. However, this health condition is more prevalent during the adolescent years between the ages of 12 and 18.

Acne develops because of the colonization of the skin’s sebaceous glands by a type of bacteria. These microorganisms block the pores of the skin, resulting in skin inflammation. This can manifest as pimples and skin rashes. It is possible to eliminate acne altogether using meticulous skin health regimens and careful management. If not, at least, the severity can be further reduced or minimized[1].

There are two principal causes of acne. We already identified one of them – inflammation. The other is oxidative stress. Both of these processes are susceptible to the anti-inflammatory action of cannabidiol. This makes CBD oil a very potent treatment against acne.

In 2014, the Journal of Clinical Investigation presented a study that focused on CBD oil’s anti-acne benefits. The scholarly article showed that CBD possesses strong sebostatic properties.

Cannabidiol exerts its anti-acne effects on the immune system through immune-modulation. It slows down the ability of the acne vulgaris [2] bacteria to grow and proliferate without exerting any untoward action on surrounding tissues.

In 2017, another study discovered that CBD can alter acne conditions through interaction with the endocannabinoid system. It revealed that such an interaction was fast and provided dramatic results. This translates to improved immune system efficiency in fighting and eliminating the bacteria that cause acne.

The endocannabinoid system plays a very important role in the proper function of the skin’s epidermal layer. It serves as the skin’s first line of defense against pathogens. This makes the skin an important part of the human immune system.

In 2009, clinical trials show that the human skin is a complex organ that involves neurologic, endocrine, and immunologic functions [3]. It also serves a critical role in the optimum functioning of the endocannabinoid system. Current medical research demonstrates the ability of CBD to target the receptors of the endocannabinoid system. This eliminates acne as well as other skin conditions.

As such, transdermal and topical preparations of CBD are effective treatment regimens for acne. The compound can also hasten the speed of healing while also preventing acne scar formation. Cannabidiol preparations have also been shown to remove existing scars brought about by acne.

There are many scholarly endeavors that support the role of CBD in accelerating wound healing. These studies also support the observation that CBD can eliminate dermal scarring [4]. These CBD effects facilitate the remodeling of the human skin, allowing it to become more resistant against acne vulgaris bacterial colonization. This makes cannabidiol products excellent alternatives to conventional acne treatments.

Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD) are two different yet associated mental conditions. These conditions feature unwanted behaviors like inability to focus, impulsivity, and lack of concentration. People with ADHD get diagnosed early in their lives. They often require treatment that includes stimulants and other medications. Sadly, many of these preparations come with nasty side effects.

Fortunately, cannabidiol has been shown to be a good alternative to conventional ADHD treatments. A 2017-published research demonstrated that cannabidiol is able to offer symptomatic relief among individuals with ADHD.

The study focused on the effects of oral CBD spray on two ADHD symptoms: poor focus and incidence of hyperactivity. The study utilized experimental and control groups to ascertain the accuracy of the results. The research revealed that CBD spray can improve focus [5] and reduce hyperactive episodes in individuals with ADHD.

In 2018, study investigators found a strong relationship between the body’s endocannabinoid system and the emotional processes of the human brain [6]. The study aimed to investigate further applications of cannabidiol products.

There are also cannabis sativa plant extracts other than CBD that can improve the processing and integration of memories. These phytocannabinoids provide additional hope to individuals with ADHD, allowing them to process and retain information in a faster and more efficient manner.

Neuroimaging studies also provide adequate support to the ongoing observation that CBD is good for brain function. These imaging studies focus on the different chemical interactions that occur between the brain and cannabidiol. The results show overall brain function improvement. Clinical evidence show that regular use of CBD can help alleviate anxiety. Anxiety is a factor that often exacerbates the symptoms of ADHD and ADD.

Cannabidiol can assist in the management of ADD and ADHD symptoms [7] without the risk of side effects.

Addiction is a condition that can have either neurochemical or psychological basis of causation. Each of these causes can present with their own symptoms and health conditions. There are numerous factors that can play a role in the development of addiction. However, one theme is very common in any type of addiction – it is very challenging to treat.

Cannabidiol has been shown to have the potential to aid in the management of addiction. Studies show that cannabidiol interacts with the brain. This interaction can lead to the mitigation of the neurological effects of addiction at the very root.

The Taylor & Francis Substance Abuse Journal published a 2009 study about the possible use of cannabidiol in the management of addictive behaviors. The study posits that CBD is an effective substance that can help treat drug addiction [8] and other types of addictions.

Science reveals that drug addiction is due to the interplay of different neurochemical factors. These factors affect human behavior in a negative way. Cannabidiol interacts with certain parts of the brain while also cooperating with the endocannabinoid system. The results show that CBD is a useful treatment option for any kind of addiction.

At least 13 studies have been conducted to ascertain the effects of cannabidiol on addiction. These studies focused more on the efficacy of CBD oil in addiction treatment. The investigations show that CBD is effective in the management of addiction to cocaine, psychostimulants, and opioids.

There are medications that can have a negative effect on the human body if they were stopped immediately. For example, morphine and other opiates can produce “abstinence syndrome”. This is a life-threatening condition which individuals want to avoid at all cost.

The “abstinence syndrome” is best known in terms of withdrawal symptoms. These can include shaking [9], teeth chattering, and cramping. Using CBD oil can help prevent the occurrence of these withdrawal symptoms. Other studies also show that CBD can prevent relapses.

The Journal of Neuropsychopharmacology published in 2018 a study that showed the ability of CBD to reduce addiction impulsivity. As such, cannabidiol is an effective tool for supporting ongoing efforts to eliminate addiction.

AIDS stands for Acquired Immune Deficiency Syndrome and is a serious disease that became popular in the last few decades. It comes from HIV (or Human Immunodeficiency Virus), which is untreatable. Once the disease progresses to AIDS, it is dangerous and life-threatening.

HIV/AIDS attacks the immune system and modern medicine has still not found a cure for it. When patients are unaware of their HIV status or do not go for treatment, they can suffer from cancer or infections.

Latest research has shown, however, that CBD and similar cannabinoids may be a vital part of an effective treatment [10] for HIV/AIDS. According to these studies, patients who use cannabis on a recreational basis have a much lower viral load compared to those who do not use cannabis. This implies that cannabis can improve the effectiveness of their treatment.

Beyond HIV/AIDS, research into CBD points to it being effective against immunodeficiency viruses. In 2011, clinical trials have provided strong evidence of CBD reducing inflammation due to immunodeficiency viruses. Beyond that, it prevents its quick spread throughout the body [11].

Other benefits of CBD use by patients with immunodeficiency viruses have been identified. Specifically, evidence has pointed to their brain function improving. Literature review and analysis support this, as regular use of CBD has been linked to better cognitive function, attention, memory, and executive functioning [12] as well.

Immunodeficiency viruses like HIV/AIDS damage the immune system greatly. The great thing is, CBD interacts with the endocannabinoid system so that the immune function is boosted. Thus, taking cannabinoid products has the potential to reduce the symptoms of HIV/AIDS and even bring these patients back to their normal healthy lifestyle.

Lastly, CBD will reduce any inflammation and stop any neurocognitive disorders that are the side effects [13] of undergoing treatment.

ALS is short for Amyotrophic Lateral Sceloris. It is a motor neuron disease wherein patients experience a whole range of symptoms that can debilitate them. This is because ALS affects the nerve cells in both the brain and the spinal column, affecting the rest of the body. Worse, it is fatal for everyone and there is no cure for this condition.

Currently, patients with ALS take drugs that can manage their ALS. One of them is Rilutek. Unfortunately, this drug has many severe side effects that can affect the patient’s quality of life. For example, they may report nausea, chest pain, and stomach pain, among others.

For these patients, cannabidiol is a promising treatment, with several trials proving that it can help manage the condition without the bad side effects.

ALS patients see many different effects on the brain like mitochondrial cell dysfunction, protein aggregation, and oxidative stress. This can bring a lot of suffering to the patient, such as inflammation within their bodies.

CBD can help deal with the inflammation because it is a powerful anti-inflammatory agent that reduces oxidative stress. It has been proven many times to be able to minimize inflammatory response. Logically, it makes it effective as a treatment for ALS.

In 2016, clinical tests into CBD and similar cannabinoids have shown their effectiveness in slowing down the progression of ALS and reducing the symptoms associated with it. Patients who have reported positive effects have taken CBD on a regular basis.

Specifically, the results of the clinical trial indicate the CBD has lowered the inflammation in the brain and lessened oxidative cell damage. This has significantly improved the quality of life of ALS patients. Moreover, they reported relief from common symptoms like drooling, depression, poor appetite [14], and chronic pain.

As with ALS, CBD has been proven by earlier studies to be effective against diseases originating from neuroinflammation. It has also been successful in protecting brain cells against many neurodegenerative disorders [15].

Another neurodegenerative disease that can be treated by CBD use is Alzheimer’s disease [16]. Unfortunately, doctors or researchers have not discovered the root cause of Alzheimer’s, but like ALS, patients experience neuroinflammation and oxidative stress in the brain. CBD has been proven to be an effective treatment against Alzheimer’s.

CBD helps against Alzheimer’s in many ways, like decreased inflammation of the brain cells, restoration of healthy brain function, as well as other neuroprotective health benefits.

The research on CBD use to treat Alzheimer’s is extensive and strong. This is because it has been tested on real humans as opposed to being tested only in the lab. Thus, the effects of this treatment can be backed by solid research.

Similar research is also being done with cannabidiol and Alzheimer’s, conducted by doctors and other medical professionals to discover if hemp oil extract is truly beneficial for the treatment of neurodegenerative disorders. This is to support the mounting evidence of using CBD for Alzheimer’s.

In 2010, a thorough review of existing clinical data on CBD and Alzheimer’s has compiled more than 50 studies. A meta-analysis has identified that CBD can help with treating Alzheimer’s and other similar neurodegenerative disorders like dementia [17] and Parkinson’s disease.

Another study in March 2018 strengthened the case for CBD use for Alzheimer’s patients. The results showed that CBD oil brings neuroplasticity health benefits, plus it stops the induced neurotoxicity associated with the disease. Thus, deficiencies in the hippocampus region are reversed and patients see improvements in the brain’s long-term memory [18].

This eating disorder, also called anorexia nervosa, is considered to be a psychological disorder that can lead to serious health problems. Treatment in many cases is also complex and difficult, as it may involve patients taking in psychiatric drugs like SSRIs. Unfortunately, these medications have been linked to a long list of debilitating and life-altering side effects.

Thus, patients with anorexia struggle to recover because of these severe side effects of this unsuitable medication. On the other hand, cannabidiol and CBD are proving to be a promising treatment for those suffering from anorexia. The benefits include addressing the root cause of the disorder, as well as reducing incidences of relapse, which happens often to these patients.

A comprehensive meta-analysis has been published in the Journal of Clinical Psychopharmacological Neuroscience in 2017, exploring the use of medical cannabis extracts to treat psychiatric disorders. There were, specifically, benefits of the use of CBD oil on cases of anorexia [19].

Beyond this, 2 independent studies have explored the impact of using CBD to treat anorexia nervosa. In all, 30 individuals took part in these studies who have been diagnosed with the psychological condition. In some of the trials, the participants were given 30mg of medical cannabis every day.

The trials have led to positive results, specifically in promoting weight gain and developing normal eating habits after undergoing 2 treatments of cannabis oil lasting 4 weeks each.

One of the associated benefits of cannabidiol is its ability to work as an anxiolytic, meaning it helps manage symptoms of anxiety that are also associated with anorexia.

Further trials have also shown that CBD is an effective treatment for anorexia-linked to chemotherapy-induced anorexia. Thus, patients who have trouble eating while undertaking cancer [20] treatment will find relief with this treatment.

If there is one answer to all bacterial infections, that would be antibiotics. Antibiotics are a go-to medicine that help kill bacteria which causing a multitude of illnesses. However, with the widespread use of antibiotics, doctors are starting to be concerned with its effects on people.

One growing concern in the medical industry is the resistance of some bacteria to antibiotics. Take note, these bacteria are the same ones that are being treated with antibiotics. But as time passes, they evolve into antiobiotic-resistant bacteria making it harder for doctors to treat them. For now, doctors are increasing the dosage or giving stronger antibiotics. But of course, this is only a temporary solution. Over time, these bacteria will be fully antiobiotic-resistant [22]. That is why doctors and scientists are starting to look for alternatives to prevent this from happening.

Fortunately, there is a more sustainable solution that the medical industry has discovered. This is through the use of cannabis extract. Cannabis, most commonly known as CBD, comes from the cannabis sativa plant. This plant contains five cannabinoid compounds such as cannabidiol, Delta (9)-tetrahydrocannabinol, cannabinol, cannabigerol, and cannabichromene. These compounds are known to have powerful antibiotic properties [21] that can be as effective as the antibiotics doctors use today. Not only that, CBD can also fight against bacteria that are immune to antiobitics or methicillin.

Apart from being a strong alternative to antibiotics, CBD has a number of anti-inflammatory and psychological health benefits. Although this area is still not fully investigated by scientists and doctors, the number of advantages for using CBD makes it a good candidate for future medical use.

If there is a downside to CBDs, that would be the lack of research needed for the medicine to be commercialized. However, a study in 2008 has shown that cannabinoids were able to act as strong antibiotics in spite of scientists not knowing how.

Nowadays, it is not uncommon for people to experience anxiety. Anxiety is a disorder in which people feel nervous and uneasy during certain social events. This is caused by a wide number of triggers ranging from public speaking to overthinking. It is also known as generalized social anxiety disorder. When a person experiences anxiety, he or she will find it difficult to think properly or to do some of their usual tasks.

Since anxiety is a psychological condition, it is often treated with both therapy and medicines. In terms of therapy, it can range from pyschologist visits to breathing exercises. On the other hand, medicines like SSRIs or selective serotonin reuptake inhibitors are given to patients to lessen the effects of anxiety. But the downside to taking SSRIs is that it is not devoid of side effects to the point that the side effects [23] become as difficult as anxiety itself.

But there is an alternative to SSRIs. Several clinical studies have shown that CBD oil and cannabidiol are great alternatives to SSRIs. They have anti-anxiety properties that help manage anxiety disorders without the trouble of getting side effects. More than that, it works by interacting with the production of serotonin in the brain. CBD interacts with the cannabinoid type-1 receptor to reduce the effects of anxiety in individuals.

In an investigation conducted in 2011, a group of individuals were given CBD oil prior to giving a stimulus that will trigger anxiety. The study showed that compared to the control group, the group given with CBD oil had lower stress levels [24] and controlled serotonin production. They were also able to exhibit calmness when they were asked to speak in front of a crowd.

Several more clinical studies are being done to prove that CBD oil is useful for managing anxiety disorders and other psychological problems such as panic disorders and obsessive-compulsive disorder [25].

When it comes to the cardiovascular system, there are many diseases that can arise. One such disease is atherosclerosis. Although a mouthful, atherosclerosis is a simple disease that can cause complex complications. In this condition, plaque builds up in the arteries of the body which disables the oxygen-filled blood vessels to spread oxygen all throughout the body. Since oxygen is required for the body to function, a lack of oxygen can lead to serious health conditions.

Medication is given to those who have atherosclerosis. Patients are given Angiotensin-Converting Enzyme (ACE) that help relax the blood vessels of the body. Although this helps in calming the blood vessels enough to provide oxygen to the body, ACE does not prevent nor cure the root cause of atherosclerosis.

Fortunately, atherosclerosis is found to be cured by cannabidiol. In past studies conducted in 2006, CBD was seen to help manage inflammation [26] and to treat atherosclerosis. To add to that, a 2009 clinical study held in Prague showed that endocannabinoids were able to improve the health of those who have Atherosclerosis [27]. The reason for this is that the body has an endocannabinoid system that aids the immune system. So when endocannabinoid is given to a patient, the immune system can be strengthened to reduce the effects of atherosclerosis.

A most recent study in 2011 also shows that CBD intake can reduce oxidative stress. This, in turn, will help the blood vessels deliver and give oxygen to the different body parts. Overall, the use of CBD will not only reduce the stress levels of the blood vessels, but it also has anti-inflammatory properties that will aid the immune system in fighting the production of plaque in the arteries. Unlike the ACE, CBD now looks as though it is the cure that doctors are looking for to help patients of atherosclerosis [28].

Part of growing old is getting a few health conditions that can limit how a person moves and performs daily tasks. If there is one health condition that comes with old age, that would be arthritis. Arthritis is a popular systemic condition that affects at least 70% of the elderly population. As people reach the age of 50, the chances of getting arthritis become high.

Arthritis is caused by the swelling of the cartilage and connective tissue in the body. However, the swelling is only the immune system’s response to oxidative stress which refers to an imbalance of the toxins in the body. When the oxidative stress is high, the immune system reacts by causing a swell in the connective tissues. This is why some people complain about joint or bone pains [29].

Another cause of arthritis is inflammation. Fortunately, doctors have realized that CBD oil has anti-inflammatory properties that help in reducing the pain caused by arthritis. Moreover, CBD oil has shown to be a perfect alternative to nonsteroidal topical treatments being used by people who suffer from this health condition.

There are many advantages to using CBD oil, but treating arthritis is one of the most popular. This can be attributed in the many studies conducted that prove CBD oil as the cure for those who have arthritis. In one clinical investigation held in 2017, CBD oil was proven to help in managing even the early symptoms of arthritis. These symptoms include joint pain, joint deterioration, soreness, and inflammation. Add to this the fact that a 2016 study proved that CBD oil does not have to be injected nor ingested in order to show results. Topical treatments are enough to show the rapid effects of this cure.

Therefore, CBD oil can be used to help alleviate the pain caused by arthritis [30]. In the long run, it could also be an alternative to curing those who are diagnosed with arthritis.

During childhood or even adulthood, a number of people experience swelling in their respiratory system that makes it hard for them to breathe. This condition is commonly known as asthma.

Asthma is a respiratory condition wherein the pathways of air swell or get inflamed causing difficulty in breathing. Notice how asthmatic people have an inhaler with them that helps unblock those passageways. There are also instances where medication is required to allow proper breathing [31]. Some medication includes corticosteroids or Xolair.

Although these medications are effective, the downside to these is unwanted side effects. Some side effects include weight gain, appetite changes, and mouth lesions. It is even possible to have gastrointestinal issues due to the strength of the medicines. To be able to avoid these side effects [32], a better alternative to these medicines should be available to people diagnosed with asthma.

One alternative is CBD. Over the past decade, studies on CBD have shown a number of health benefits including asthma treatment and management. As far as asthma is concerned, CBD is a powerful drug that can alleviate the inflammation that occurs in the air passageways. In turn, asthma, and even allergic asthma becomes treated.

Just this year, a study about cannabidiol showed that it can effectively treat those who have asthma. This study was conducted by five pulmonary research departments around the world. It also showed that CBD can help manage the production of collagen fiber, an asthma-inducing substance. The added advantage of CBD here is that the study was able to prove that CBD gives a faster healing time [33] for those with asthma. In a short amount of time, air passageways will be cleared of inflammation and blockages.

The 2019 study can further be supported by a research done in 2015 which shows the changes in cytokines levels with and without CBD. The latter demonstrates that cytokines, a substance produced by the immune system which causes inflammation, is lowered when a person takes the right CBD dosage.

Autism is one of the psychological disorders that have different versions. This is because autism varies between individuals who are diagnosed by it, hence the term “spectrum disorder”. Needless to say, since symptoms of autism vary, treatment should also vary.

Up to now, there is no known cure for autism. However, there are medications that allow people with autism to manage their disorder [34]. In fact, there is now a range of treatments from behavioral therapy to prescription drugs. But the problem with prescription drugs is that they can be too strong for the patient that the patient experiences some unwanted side effects. Imagine having an autistic child taking a strong medicine just for the sake of managing their condition.

This is why doctors and researchers alike have looked into the possibility of CBD and cannabidiol products in treating autism. Fortunately, they were not dismayed with the results. Based on a study that used 900 individual cases, those who were given a regular dosage of CBD were able to exhibit a “dramatic improvement” in their behavior. This goes for all patients with different kinds of autism. The study was able to conclude that similar symptoms of autism were treated by a regular dosage of CBD.

But apart from this study, there is not a lot of research done between CBD and autism. In fact, it is still in its early stages in terms of clinical trials. The closest study about these two topics included animals for clinical trials [35]. In this study published in 2017, the brain functions associated with autism reacted to endocannabinoid [36] which is a substance found in CBD.

Nonetheless, CBD is showing promising results in terms of helping reduce autism symptoms in a wide variety of cases. As early as now, it can help pave the way for reducing the symptoms that make autism difficult to manage.

Bipolar disorder is a psychological disorder that has captured the interest of a lot of people. Aside from the fact that attitudes and personalities sway from one side to another, bipolar disorder differs from one person to another. Some terms used to refer to bipolar disorder are manic depressive illness and bipolar affective disorder.

Aside from having different manifestations on different individuals, bipolar disorder also varies in complexity, symptoms, and difficulty. Naturally, a more complex version of bipolar disorder requires a stronger dosage of medicine. Sometimes, the dosage or the medicine itself is too strong that it can cause side effects to the individual. A common pharmaceutical medication used in treating complex bipolar disorders is called antipsychotic [37] medication. This potent medication, however, triggers side effects in some people.

On the other hand, cannabinoids like cannabidiol are known to have the same potent properties with antipsychotic medicines. But unlike the latter, the former does not trigger side effects harmful for those who have autism. Cannabinoids have health benefits that help give a sedative-like effect on people with bipolar disorder. In this way, their symptoms can be somewhat manageable without them feeling hazy or downcast as side effects of strong medication.

At first, CBD studies showed inconclusive findings on how effective it is in treating bipolar disorders. However, more recent clinical investigations showed the effectiveness of CBD in managing bipolar conditions without the side effects that traditional medicines [38] give. To add to that, a study conducted in 2005 showed that CBD gives anti-anxiety benefits that are helpful for those who have both bipolar and anxiety disorders.

Another clinical investigation of CBD and bipolar disorders[39] was published in the Journal of Psychiatry and Neuroscience. This investigation proves that those who have been given marijuana with large amounts of CBD for medical purposes are able to have reduced effects of bipolar disorder.

Cancer has always been a threat to the lives of so many people. Rich or poor, young or old, cancer doesn’t choose anyone. And what makes cancer harder to deal with is that it carries with it a variety of symptoms that bring people to a lot of pain.

But looking at cancer symptoms more closely, there are some that are similar across different kinds of cancer. Usually, cancer starts out as a few pangs inside the body. A person might experience pain somewhere near the stomach or near the place where cancer has started. A person can also experience exhaustion and weakness during the time that cancer is starting to develop. While these symptoms are common across different kinds of cancer, it doesn’t mean that they should be left untreated.

This is where cannabis extracts are needed. Recently, there has been a lot of debate regarding the use of cannabis plant in treating cancer [40]. Nonetheless, CBD has been shown to help improve the overall health of cancer patients. This is because cannabinoids which are present in CBD can interact with the human body’s endocannabinoid system which plays a part in the development of cancer cells. Previous studies have shown that cannabinoids help modulate the production of cancer cells thanks to its interaction with the endocannabinoid system.

Still, there is a lot of controversies involving the use of cannabis to treat even the symptoms of cancer. Some claim that there is not enough studies and tests done to prove the effectivity of CBD to the illness. However, the Oncotarget Open Access Impact Journal can show that extensive research was already made. There is even a report explaining all the research initiatives that link CBDs with cancer cure or alleviation.

Unfortunately, today, CBD has not yet been commercialized for treating cancer. But the good news is that this is already in the works and there is a way to kill cancer cells [41].

There are different types of health problems that can affect the digestive system. Examples of these include celiac disease, stomach ache, and lactose intolerance. There are those that are quite serious that they turn into cancer, like Crohn’s disease. What is common among these disorders of the gastrointestinal system is that the inflammatory response of the immune system plays a major role in their development.

Clinical investigations and other scholarly activities underscore the impact of using CBD and cannabinoids in the health and function of the human gastrointestinal tract and digestive system. These studies point to the link between the GI tract and the endocannabinoid system. A 2005 study determined that one of the effects of cannabinoid receptors is the relaxation of the esophageal sphincter. These receptors serve to modulate the production of gastric acids [42] while also slowing down motility.

There are also research findings that establish the usefulness of CBD in the prevention of common disorders of the GI tract. One such health condition is acid reflux disease. These research studies determined that CBD is able to regulate the synthesis of certain molecules in the body. The modulation of these compounds can bring about a desired balance in pH levels throughout the gastrointestinal tract [43].

In addition to its role in the establishment of digestive pH balance, CBD can also enhance the body’s ability to produce critical digestive enzymes. These compounds are important in ensuring that the human body is able to absorb all the bioactive nutrients that the cells need. There are also studies that show the interaction between CBD and the GI tract can lead to enhanced metabolism. This results in increased energy levels, facilitate healing [44], and improve overall immune system function.

One cannot overstate the relationship between a healthy functioning digestive system and a robust immune system. Cannabidiol products can improve the functioning of the digestive system, helping ensure an improvement in overall health [45].

CBD products are, thus, ideal for the management of irritable bowel disease, inflammatory bowel disease, and other disorders of the digestive system. It can also modulate a person’s appetite.

Depression is a type of mood disorder wherein people can go through varying levels of severity. There are those who may experience milder forms of depression, allowing them to go through the condition without difficulty. However, there are also those who suffer from serious bouts of depression. This can be debilitating, preventing them from enjoying life and performing their everyday tasks.

Individuals with depression often undergo behavioral therapy. However, some types of depression may also respond well to antidepressant medications. The problem with such medications is that they’re replete with side effects. These include depression, suicidal thoughts, dizziness, constipation, and digestive issues, among others. Antidepressant medications are effective, but can have a negative impact on one’s health.

Cannabidiol and other cannabinoid products can provide a wide range of benefits that can be instrumental in the alleviation of the symptoms of depression. These products can deliver near-instant results without causing any unwanted side effects.

In 2010, clinical trials assessed the efficacy of CBD oil on depression. These studies revealed that CBD has potent psychiatric benefits in terms of its anti-anxiety or anxiolytic properties. Furthermore, cannabidiol has been shown to possess antidepressant properties [46] that are not only effective, but also fast-acting.

In August 2018, a study found that CBD can also have an impact on the brain’s serotonin levels. The research revealed that cannabidiol can help improve the function of the serotonin system. This can help elevate mood while also preventing many of the symptoms of depression [47].

Other researches in 2018 point to the ability of cannabidiol to provide immediate and fast-acting relief from depressive symptoms. These scholarly endeavors identified the specific area of the brain where CBD exerts its antidepressant effects. Clinical investigations showed that cannabidiol target the prefrontal area of the cerebral cortex [48], boosting brain activity and improving mood.

The good news about using cannabidiol in the management of depression is that one is not limited to a particular route of administration. CBD for depression can be available in the form of vapes, tinctures, and gummies. Regardless of the route of administration, these CBD presentations provided instant relief from depression without untoward effects.

Diabetes is a health condition that develops because of the body’s inability to process sugar or glucose. Type I diabetes occurs because of the body’s inability to create and use insulin. Insulin is the hormone that facilitates the movement of sugar in the blood to the cells. Type II diabetes [49] occurs because of an overexposure to insulin.

Regardless of the type of diabetes, the main problem is the inadequacy or failure of the body to regulate sugar levels in the blood. This can have serious implications for general health. When left untreated, diabetes can lead to serious and life-threatening conditions. It can lead to the amputation of the limbs and may also cause blindness.

Research investigations reveal that cannabidiol can be a great adjunct to diabetes management. In 2012, a study revealed that the endocannabinoid system has a direct link with diabetes. To be more specific, the study showed that oxidative stress can have a profound effect on the development of diabetes.

In 2016, pre-obesity mice were administered with cannabidiol supplements. The results revealed that these laboratory mice showed a reduced risk of developing diabetes [50] than mice that did not receive CBD supplements.

A late 2018 clinical research revealed that CBD can help protect the brain and the body against inflammatory processes. Such an effect can help reduce the severity of diabetic symptoms.

Cannabidiol has been proven to be effective in the control of diabetes. A placebo-controlled, double-blind randomized clinical trial in 2016 revealed that diabetic individuals [51] who use cannabis extract show greater control of their blood sugar levels [52]. While the results require further investigation, it does offer hope to millions of diabetics.

It is important to realize that cannabidiol is not a cure for diabetes. However, it can be a great tool for the management of the various symptoms that are inherent in diabetes. This way, diabetic individuals can still improve their health and wellbeing.

The human endocrine system controls the different organs that produce and secrete hormones. As such, a problem in any of these organs can lead to an endocrine problem or a hormonal issue. Examples of these conditions include hirsutism, Addison’s disease, hypothyroidism, growth hormone deficiency, and many others.

What is interesting is that the endocrine system is also related to the endocannabinoid system. It is through this relationship that CBD and cannabinoid products are able to exert their beneficial effects on the human endocrine system.

A clinical study in 2015 revealed that CBD can modulate the function of different organ systems in the body. To be more specific, the study showed that cannabidiol can have an effect in the way growth hormones, oxytocin, prolactin, and thyroid hormones are released. CBD and similar products can also regulate the activities of the hypothalamic-pituitary-adrenal axis [53].

This suggests that exogenous cannabinoids can help in the management of a variety of endocrine disorders. Not only is it possible to manage the symptoms of these disorders, it is also possible to prevent such disorders from occurring.

For example, cannabis plant extracts have been shown in many clinical trials to have an effect on hypothyroidism. Cannabidiol and other phytocannabinoids can minimize the effects or impact of endocrine disorders.

Thyroid carcinoma, on the other hand, is now possible to prevent with the use of cannabidiol. Modern research continues to dig deeper into the many benefits of CBD [54] on the endocrine system [55]. It may still be in its infancy, but the potential is there.

Epilepsy encompasses a wide range of disorders and health conditions that share one very unique trait: unpredictable seizures. Epilepsy can happen to anyone, regardless of age and status in life. This condition can also be challenging to treat.

The conventional method of treating epilepsy is by administering a variety of medications. The issue is that many of these drugs also possess side effects that can have a negative impact on one’s health. Examples of side effects that these medications produce include depression, sleepiness, sleep apnea, dizziness, and weight gain.

Clinical experiments show that cannabidiol can provide immediate results for individuals with epilepsy or any type of seizure disorder.

There is an extensive body of evidence pointing to the use of cannabidiol and cannabinoid products in the management of seizure disorders. The majority of the research points to the role of CBD in the elimination of the risk of developing seizure disorders. It also helps improve overall quality of life.

The Journal of Epilepsy Research published in 2017 a meta-study [56] about the role of cannabidiol in the treatment of epilepsy. The study showed that cannabidiol can prevent seizures without any untoward side effects or adverse reactions that some people may associate with tetrahydrocannabinol.

Clinical data also suggest that CBD oil possesses anticonvulsant properties. This is in addition to its analgesic and anxiolytic characteristics. Other studies indicate the importance of CBD in the prevention of grand mal seizure [57] episodes. For this to be effective, however, it is important to administer CBD right at the onset of the seizure. The implications are that individuals with seizure disorders now have a better chance of eliminating the associated symptoms.

Research evidence shows that cannabidiol is a powerful tool against epilepsy [58]. What makes it more interesting is that it exerts its anti-seizure effects without any side effects.

This is a debilitating disorder that can produce a variety of unpleasant symptoms. These can include memory loss, musculoskeletal pain, fatigues, mood disorder, and loss of sleep. Treating fibromyalgia often includes the administration of drugs. Unfortunately, many of these medications cause numbness, increased pain sensation, and sleep difficulties.

Since late 2008, medical researchers have worked to determine the benefits of cannabidiol in the management of fibromyalgia. There is now convincing evidence that show CBD oil’s effectiveness in the alleviation of pain syndromes associated with fibromyalgia [59].

There is a separate study in 2018 concerning the effects of medical marijuana on fibromyalgia symptoms. While this is not cannabidiol, the logic is that cannabis can be effective in the management of the various symptoms associated with fibromyalgia.

A clinical trial conducted in 2016 revealed that THC-free cannabidiol can be an excellent adjunct to conventional fibromyalgia treatment. Seventy-two participants in the study were given controlled doses of synthetic cannabinoid. The results revealed that the study participants who received synthetic cannabinoids reported a 50 percent reduction in their pain experiences.

Fibromyalgia is also known for producing chronic pain. Cannabidiol can also be effective in managing such types of pain. The takeaway in these studies is that CBD oil is an effective treatment for musculoskeletal disorders without the risk of unwanted side effects.

Glaucoma is a condition of the human eye whereby there is degeneration of the optic nerve. If this goes untreated, the individual can go blind. Early detection can help prevent further eye damage and potential vision loss. This also helps pave the way for a more efficient treatment of glaucoma.

Blindness secondary to glaucoma is permanent. Conventional treatment approaches include the use of eye medications and laser surgery. Glaucoma causes extreme pain and nausea [60]. It is for this reason that individuals with glaucoma are often given powerful painkillers. The problem with such an approach is the potential of these painkillers to cause dependency and possible addiction. There are other side effects, too.

Medical marijuana is one of the most potent alternative painkillers in the medical field today. The only problem is that medical marijuana can also have its fair share of side effects.

Cannabidiol and other cannabinoid products can exert analgesic properties that are similar to medical marijuana. However, these do not cause intoxication, dependence, or any other side effect. This makes CBD and similar products a more viable option for people with glaucoma [61] to manage their pain syndromes.

Clinical trials in 2006 were able to show the effectiveness of CBD in the management of pain. Five milligrams of CBD extracts delivered via the sublingual route can reduce pain levels while minimizing the symptoms of glaucoma.

The British Journal of Ophthalmology published a clinical study in 2004 about the effects of CBD oil on intraocular pressure. This is the main cause of pain in glaucoma. The same study revealed that CBD oil can also lower blood pressure. Overall, cannabidiol is a good alternative to conventional pain medications in the symptomatic management of pain related to glaucoma.

Heart or cardiovascular disease is the number one killer among Americans. Heart disease can be secondary to different health conditions and potentiated by a host of risk factors. Faulty dietary practices, overweight, absence of physical exercise, and smoking are some of the more common risk factors of heart disease.

The sad thing about cardiovascular disease is that it can be very challenging to treat and manage. The pragmatic approach to managing heart disease [62] almost always involves the use of powerful drugs. Many of these can cause equally-serious side effects.

Cannabidiol can be a much better choice in the management of heart disease. It doesn’t cause any unwanted side effects or adverse reactions while still ensuring its therapeutic effectiveness.

One of the principal causes of heart disease is inflammation. Several meta-studies suggest that systemic inflammatory conditions can increase the risk of developing heart disease among susceptible individuals.

CBD oil possesses powerful anti-inflammatory properties, allowing it to reduce inflammation before this can have its negative impact on the cardiovascular system.

A clinical study in 2017 supports this assumption. The American Society for Clinical Investigation Journal published the study that showed the efficacy of a single dose of CBD on heart health. The research established that cardiovascular health [63] can be improved with a single dose of cannabidiol.

There is also a 2007 study that shows that CB1 and CB2 receptors can play a role in cardiovascular health [64]. Additional studies reveal that cannabidiol can reduce oxidative stress and return the full function of the heart to normal. CBD can also dampen inflammatory processes that may occur anywhere in the cardiovascular system.

Regular use of cannabidiol can help in the management of cardiovascular [65] diseases. It can also assist in the prevention of heart disease.

Cannabidiol is an effective treatment for a number of neurodegenerative disorders. One of these is Huntington’s disease. This disorder can affect an individual’s physical and mental abilities. It is almost similar to Alzheimer’s disease when it comes to its progression as a disease. Huntington’s disease often worsens over time. What is important to recognize is that inflammation can worsen it. This is especially the case in oxidative stress-related neuroinflammation.

Individuals with Huntington’s disease often experience a decline in their cognitive functions. The sad fact about this disease is that there is no treatment or cure yet. This is why medical and clinical specialists are working round-the-clock to identify potential treatment options. This includes cannabidiol and cannabinoid products.

One of the earliest studies identifying the potential benefits of CBD on Huntington’s disease is in 1991 [66]. The study showed minimal benefits. However, it did open the door to other researches since the clinical investigation also revealed CBD did not produce any side effects.

New research suggests that CBD can help prevent the development of Huntington’s disease, while also exhibiting the potential to treat existing ones.

In 2018, the Frontiers in Pharmacology Journal [67] published a meta-analyses of all research studies conducted related to Huntington’s disease. The study revealed that cannabidiol can protect the brain cells of Huntington’s disease patients by as much as 84 percent. Huntington’s disease causes death in the brain cells. Administering CBD has been shown to afford 51 to 84 percent protection against brain cell death.

The same study revealed that CBD oil can slow down the progression of brain inflammation. This can contribute to the reduction in the amount of brain cell death. This also helps in the promotion of more efficient cellular healing. In some instances, cannabidiol has been shown to improve the motor control of individuals with Huntington’s disease.

Additional research into motor control disorders and cannabidiol suggests that CBD can protect the integrity of neurons in the brain. Its neuroprotective properties [68] make cannabidiol a worthy option in the management of Huntington’s symptoms.

When added with tetrahydrocannabinol, CBD can also minimize the tendency for shaking and tremors [69]. This is from the results of a study conducted in 2013.

Cannabidiol possesses powerful anti-inflammatory properties. This is one of the secrets to CBD’s many health benefits. It is how the plant extract can help the human body since many of the disease conditions that man experiences are almost always the result of inflammatory processes.

While inflammation is the immune system’s natural response to a physiological insult, it can become serious if it is due to free radicals. The resulting oxidative stress can produce a cascade effect, leading to other more serious health problems.

Examples of health conditions that are due to systemic inflammation include Crohn’s disease, Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, arthritis, and irritable bowel syndrome, among others.

There is a mountain of evidence supporting the use of cannabidiol in the reduction of inflammation. Extensive clinical observation and testing has produced a long list of meta-studies, proving the effectiveness of cannabidiol in the management and prevention of inflammatory disorders.

The cannabis plant contains phytocannabinoids. Sophisticated research studies have been able to show that these substances can modify immune system responses in relation to inflammatory processes.

Studies show that cannabidiol regulates the production of cytokines [70]. This can help explain the effectiveness of CBD in the management of a variety of joint problems like joint degeneration and osteoarthritis. The same mechanism is also responsible for mitigating the effects of peripheral neuropathy [71].

The transdermal application of CBD appears to be the most effective route of administration to minimize inflammation. These patches allow CBD to exert its anti-inflammatory effects on the area of inflammation. This guarantees more localized management of pain and inflammation.

Since transdermal patches bypass the gastrointestinal tract, the therapeutic effects of CBD get delivered to their target areas fast. This also allows for more powerful anti-inflammatory effects.

Individuals diagnosed with kidney disease often have to undergo complicated and very intrusive treatment regimens. This is because kidney disease is a serious medical condition that can be brought about by high blood pressure, cystic diseases, autoimmune diseases, diabetes, and cardiovascular disease.

More often than not, individuals with kidney disease have to undergo regular and frequent urinary dialysis. This is to help remove the toxins that the ailing kidneys can no longer remove. Dialysis is a costly procedure and can also entail certain side effects [74].

On the other hand, using CBD can help in the management of kidney disease. Moreover, cannabidiol can reduce the incidence and severity of the symptoms associated with the treatment regimen for kidney disease.

In 2017, a clinical research study attempted to describe the impact of cannabidiol on the human kidneys. The study revealed that CBD can improve renal function without causing adverse reactions.

Among patients with kidney disease, cannabidiol is often used as a painkiller. A March 2018 study supports the use of CBD as an adjunct to the management of kidney disease-related pain syndromes.

The same study revealed that 100 mg of CBD per day is enough to alleviate the pain that patients with kidney disease experience. The same study also showed that CBD did not produce side effects or dependency issues.

There are additional researches highlighting the ability of CBD to prevent nausea, anorexia [76], and insomnia. These are some of the more common side effects of kidney disease treatments [75]. While these results are noteworthy, it is important to recognize that the investigations into the effects of CBD on kidney disease are far from final.

What many researchers are relying on is the observation that cannabinoid receptors are abundant in the human kidneys. This makes it possible for the development of targeted CBD solutions that can help treat different kidney diseases. If this occurs, then it is more than possible to improve the quality of life of patients with kidney disease.

While cirrhosis is one of the most common types of liver disease, there are other health conditions than can affect the liver. In cirrhosis, there is progressive scarring of the liver tissues. Fatty liver disease, on the other hand, features the unusual accumulation of fat in the liver.

Both cirrhosis and fatty liver disease can progress into a systemic disorder. Current treatment for liver diseases involve the administration of medications. Unfortunately, medications rely on the liver for their efficient metabolism. If the liver itself is ‘sick’, then it will be almost impossible for the body to get rid of the toxic metabolites that these medications bring. Hence, the very same medications that are used to treat liver disease may also cause further problems like weight gain, swelling, and skin rashes.

There is a new body of evidence showing the role of CBD compounds in promoting and enhancing optimum liver health and function. An Israeli study in 2011 showed that cannabidiol can boost the function of both the liver and the brain. The study underscored the relationship between the liver and the endocannabinoid system [77].

In 2014, the Liver Disease Research Center of the Saudi Arabian King Saud University Department of Medicine conducted a study to establish the relationship between CBD and fatty liver disease as well as other liver diseases. The research found that CBD can reduce the extent and severity of hepatic injuries [78].

There is also conclusive evidence showing the ability of cannabidiol to reduce the symptoms of liver damage caused by chronic alcoholism. The 2017 research underscored the capability of cannabidiol in fixing the different errors of metabolism inherent in liver disease. The participants of the study were chronic alcoholics, further suggesting the importance of CBD in mitigating alcoholism-induced liver damage. The same study revealed that CBD oil can also reduce systemic inflammation while also reducing the intensity of liver inflammation [79].

An intriguing observation from these studies is that the human endocannabinoid system can accelerate the liver disease process. However, the unique differences between endogenous cannabinoids and exogenous cannabinoids point to the role of CBD as a healing compound [80] for the damaged liver.

When one talks about metabolic syndrome, one is not talking about a single disease entity. Metabolic syndrome [81] is a collection of disorders that can have serious effects on overall health. The syndrome can also exacerbate or increase the risk of developing inflammatory conditions, heart disease, and diabetes.

There are different factors that can contribute to the occurrence of metabolic syndrome [82]. This can include high and uncontrolled blood sugar levels, high blood pressure, excess abdominal fat, and high blood cholesterol levels. Cannabidiol can help reduce the severity and extent of these health conditions, if not eliminate them. This can help minimize the risk of developing metabolic syndrome.

A large body of clinical evidence supports the use of cannabidiol and cannabinoid products in the prevention of metabolic syndrome. There are clinical data in the 2011 edition of the Handbook of Experimental Pharmacology suggesting that the endogenous cannabinoid system in the human body can create an imbalance. This can lead to the development of a variety of health conditions which can have a role in the development of metabolic syndrome.

A 2012 clinical study also provides credence to the use of CBD in managing metabolic syndrome. The results of the study posit that metabolic syndrome can occur because of the pro-inflammatory cytokines that the immune system produces.

The same study demonstrates the ability of cannabidiol to facilitate an immunomodulatory effect. This prevents the body from producing the cytochrome P450 enzyme. This enzyme system is the subject of several studies linking several health conditions to the development of metabolic syndrome.

One of the most potent effects of cannabidiol is its anti-inflammatory action. This helps reduce the risk of developing systemic inflammation and systemic health conditions that can include metabolic syndrome. Numerous clinical trials have underscored the potential of CBD oil in reducing the risk of inflammatory disorders, heart disease, obesity, stroke [83], and other metabolic syndrome-related conditions.

Cannabidiol provides benefits that encompass organ systems. And since metabolic syndrome is a kind of systemic disorder, then CBD can help in the prevention and management of metabolic syndrome.

Known as super headaches, migraines are one of the most common reasons why people lose their productivity. The pain can be so debilitating that it becomes almost impossible to function at one’s optimum levels. It is difficult to establish the exact and direct cause of migraine [84]. Science has made many attempts, but always ends up short. However, what is known is that migraine comes with two characteristic features. One is an abnormal brain activity. The second is a disruption in the efficient interaction between the blood vessels, the neurotransmitters, and the nerves within the brain itself.

Triptans are the gold standards when it comes to medications for migraine headaches. These are very effective drugs. However, like all medications, triptans can also come with side effects like drowsiness, weakness, hot flushes, dizziness, and tingling sensations.

The different processes of the human brain are linked to the endogenous cannabinoid system of the body. Hence, CBD is a viable alternative when it comes to the management of migraine headaches. There are studies that show instant relief from headaches with the single administration of cannabidiol.

In 2018, a study examined the relationship between migraines and cannabidiol as treatment. The clinical investigation revealed that exogenous cannabinoids like CBD play an important role in the unique chemistry of the brain. The research identified certain areas of the brain where receptors of the endocannabinoid system are often found. These areas of the brain are also those parts activated during an episode of migraine.

The same study also highlighted the antiemetic and anticonvulsant properties of cannabidiol. When combined with CBD’s analgesic and anti-inflammatory properties, these therapeutic benefits provide the backbone for a synergistic method of managing migraine headaches. The result is faster headache relief without the troublesome side effects.

There is also a study in 2017 whereby cannabidiol has been shown to be an effective method for treating any type of headache disorder. The research team of the University of California – Department of Psychiatry found that cannabinoids can modulate the process of disease causation in headaches. These plant extracts mirror the effects of anti-headache medications, but without their side effects.

Mood disorders are those psychological conditions that can produce inconsistent or distorted emotional states. These conditions can make it very challenging for individuals to control their social interactions and activities of daily living. Mood disorders can include both elevated and depressive states.

Managing mood disorders almost always entail the administration of medications like carbamazepine, lithium, and valproic acid. Some will also use other pharmaceutical mood stabilizes. The issue with these drugs is that they are also replete with side effects like tremors, rashes, blood pressure fluctuations, weight fluctuations, excessive thirst, and shaking.

Cannabidiol can help individuals with mood disorders manage their symptoms without fear of worrisome side effects.

The principal mechanism of action of cannabidiol in the management of mood disorders is that of an anxiolytic. There are many clinical trials and investigations [85] that support the anti-anxiety benefits of CBD oil.

In 2018, one such clinical study revealed that CBD can help prevent neurodegeneration. It can also provide antipsychotic benefits to individuals who are suffering from psychiatric mental health conditions. The study focused on the neurochemical interactions between exogenous cannabinoids and the human brain.

Researchers of the University of Newcastle on Tyne’s Department of Psychiatry also conducted a study in 2011 about the effects of CBD on mood disorder [86]. The scientific investigation demonstrated that CBD can modulate the excitation of the cerebral cortex, minimizing fluctuations [87] in the mood of the individual.

Sensory conflict is the most common cause of motion sickness. There is conflicting information coming from the inner ear and the eyes, causing the individual to feel dizzy and sick.

Like all health conditions, motion sickness can vary in severity. Most individuals who experience motion sickness can have vertigo and nausea, which leads to vomiting.

There are two types of medications that physicians prescribe to manage motion sickness [88]: marezine and Dramamine. Both can help minimize the effects of motion sickness, but can also produce side effects. These can include drowsiness, impairing the person’s ability to stay alert.

Studies show that exogenous cannabinoids like CBD can address some of the symptoms of motion sickness. While there is yet to be a study that will point to the role of CBD in modulating the neural mechanisms involved in the development of motion sickness, its effectiveness as an antiemetic still merits attention. Plus, the fact that it doesn’t cause unwanted side effects makes CBD a better alternative in the management of motion sickness symptoms [89].

The British Journal of Pharmacology published a study in 2011 about the antiemetic properties of CBD. The investigation focused on cancer therapy-associated nausea. One of the implications of the study is that cannabidiol can be an effective and powerful tool to minimize the incidence and severity of nausea associated with motion sickness.

Also in 2011, the Journal of Basic & clinical Pharmacology & Toxicology published a clinical investigation demonstrating the ability of CBD in preventing nausea. The study posits that the administration of CBD at the onset of nausea can help prevent or halt its progress.

Multiple sclerosis produces a progressive deterioration of the tissues of the central nervous system involving the brain and the spinal cord. This can lead to the development of different symptoms that can debilitate the individual. Multiple sclerosis disrupts the effective transmission of electrical nerve impulses throughout the central nervous system.

This can lead to the slurring of speech, the development of double vision, and weakness and numbness of the extremities. Blindness, bladder control problems, and chronic fatigue can also occur. There is no definitive treatment for multiple sclerosis as of the present. The medications that MS patients use are more directed towards the relief of symptoms. Unfortunately, these drugs also present with other health problems like headaches, fevers, and rashes.

Individuals with multiple sclerosis have to pay special attention to the proper care and management of their condition. Scientific papers show that cannabis is a potent source of bioactive substances that can help address many of the symptoms associated with multiple sclerosis.

There is a growing body of scientific evidence supporting the use of cannabidiol in the management of multiple sclerosis. A 2017 clinical investigation demonstrated the beneficial effects of CBD on the alleviation of MS symptoms. The study highlighted improvements in cognitive function, reduction in the incidence of psychosis, and fewer instances of cognitive impairments [90] to be the major effects of CBD on individuals with multiple sclerosis. The study also showed no side effects with the use of cannabidiol.

There are also researches that focus on the ability of CBD to facilitate recovery of mobility in patients with MS. One of the pathognomonic manifestations of multiple sclerosis is the loss of mobility in a gradual fashion. In 2018, a clinical study revealed that this process of mobility loss can be slowed down by the administration of CBD and other cannabinoids [91]. It is also posited that CBD may reverse the loss of mobility; albeit partially.

Nausea is not a disease per se. However, it may signal the presence of an underlying medical problem. Nausea is best described as the sensation of vomiting [92] plus a generalized discomfort. Headaches, migraines, medications, pregnancy, and anxiety are some of the more common causes of nausea. Chemotherapy [93] and viral and systemic infections can also produce nausea.

There are many ways by which one can manage nausea. There are over-the-counter medications as well as prescription drugs. Many of these solutions can help minimize the feeling of discomfort. However, not everyone can use such treatments because of potential incompatibility with current or existing medications.

Cannabidiol can address such issues while also helping alleviate nausea. CBD oil is the subject of numerous studies, highlighting its beneficial effects in the management of nausea.

There are two principal areas in the human brain that are responsible for regulating the sensation of vomiting. These are the chemoreceptor trigger zone and the vomiting center. The medulla oblongata contains these two distinct yet correlated areas. These also contain endogenous cannabinoid receptors, linking them to the endocannabinoid system. A 2013 study supported this observation. The European Journal of Pharmacology published the study and highlighted that use of CBD in the prevention of the vomiting response to eliminate nausea.

The investigation underscored the possibility of administering CBD to individuals who experience nausea on an as-needed basis. The same study also described the use of CBD in alleviating nausea among individuals receiving chemotherapy for cancer.

A 2011 demonstrated that 30 milligrams of cannabidiol everyday can provide relief from nausea among individuals receiving chemotherapy.

In neurodegeneration, there is a progressive destruction or breakdown of brain tissue. There are many potential causes of neurodegeneration. Examples of these include Parkinson’s disease and Alzheimer’s disease. Each of these can lead to cognitive impairments. Because the pathophysiology of neurodegenerative disorders [94] is poorly understood, they are challenging to treat and manage.

Neurodegenerative disorders [95] can present with a myriad of symptoms. These symptoms are often associated with the breakdown of neurons in the human brain. Since neurons are the functional cells of the brain, their breakdown can lead to numerous deficits in brain function.

Managing neurodegenerative disorders entails the administration of certain drugs. Unfortunately, many of these are not that effective since the actual pathophysiology of the condition is not clearly understood. What is clear is that one of the principal pathophysiologic features of these disorders is inflammation. Neuroinflammation is one of the hallmarks of neurodegenerative disorders.

CBD and other cannabinoids have been shown in many studies to slow down the deterioration of cognitive function seen in neurodegenerative disorders.

In 2009, a study showed that CBD can provide therapeutic benefits to individuals with neurodegenerative states.

Another study in 2013 revealed that cannabidiol can modify the way the brain releases the pro-inflammatory substance, cytokine. By modifying the release of cytokines, cannabidiol can help minimize the extent and severity of neurodegeneration.

Other clinical studies also show that CBD can help people with dementia. Cannabidiol can help these individuals recover some of their memory and other cognitive functions. In some cases, CBD can also promote enhanced neuroplasticity, allowing for improved memory function [96].

An individual experiencing chronic pain will not be able to manage the pain experience in an effective manner. The pain is consistent and can be almost impossible to manage. Individuals who are in chronic pain are unable to perform their everyday tasks to the optimum levels. Chronic pain is best defi ned as pain condition that is present for at least 12 weeks.

There are many possible causes of chronic pain. Injuries to the musculoskeletal system and chronic inflammation are two of the most common causes of chronic pain. Other causes include systemic disorders, blood pressure abnormalities, and digestive disorders, among others. In addition to chronic pain, other manifestations can include nausea, migraine headaches, sleep disturbances, and loss of appetite.

When a person comes from an injury or an operation, it is only natural for him to feel pain. But when the pain extends to more than 3 months, then that could be a different kind of pain.

The thing about chronic pain is that it ranges from mild pain to a very disturbing one. Those who are already experiencing discomfort are given pain medication so that they are able to carry out their daily tasks. However, frequent pain medication could give side effects [97]. What’s worse is that the individual can develop a certain resistance to current medicine.

This is why doctors are looking at cannabidiol to replace the use of strong pain relievers. CBD oil is known to have a number of health benefits and a number of clinical studies show that it has very promising properties that improve the overall health of individuals. To add to that, cannabidiol does not give any side effects, unlike traditional medicine most doctors prescribe.

In a study published in 2017 which was partly conducted by Harvard Medical School [99], CBD was proven to be an effective pain reliever [98] as compared to opioids. This study also concluded that compared to the latter, CBD did not trigger any side effects in the 90 clinical trials that were held.

Obesity has always been a growing health problem in the United States. In 2018, at least 30% of the population is considered obese and this number keeps on growing. The primary reason for obesity, studies show, is poor dietary choices by individuals. Add to that the aggressive marketing techniques created by companies that promote junk food, desserts, and alcohol, and you have the perfect formula to tempt so many individuals to keep on eating.

While the main methods of reducing obesity are to make healthier diet choices and to maintain an active lifestyle, there is no denying the benefit of taking supplements. Supplements can help reduce the chances of getting hungry by “tricking” your brain into thinking that the stomach is full. One of the supplements that can do exactly this is CBD oil.

CBD oil is slowly gaining popularity in the medical world because of its health benefits. Proven to help alleviate chronic pain and manage psychological disorders, CBD oil also promises to aid in reducing obesity. According to a few clinical trials, CBD is able to act as an appetite modulator [100]. It changes how the body reacts to appetite stimuli therefore changing the diet patterns and cravings of an individual.

To add to that, a study conducted in 2012 showed that CBD was able to limit a person’s cravings for food. This was a neuropsychopharmacological clinical trial that aimed to compare both CBD and THC in modulating the appetite of a person. This study was able to conclude that the former was a more effective method for reducing hunger urges.

Another advantage of using CBD is that it is known to reduce the production of fat cells. Fewer fat cells enable the body [101] to reduce the stored fats, therefore, reducing both the weight and the unwanted toxins in the body.

Obsessive-compulsive disorder [102], commonly known as OCD, is one of the more popular psychological disorders. It has been a buzzword for people who want everything to be neat, tidy, and organized. But contrary to what most people think, OCD is a disorder that causes compulsions and repetitive actions in an individual. This is not to say that the person loses control of their actions. In fact, the opposite is true as the brain triggers a command for the person to do certain actions for a number of times.

Since OCD is a psychological disorder, simply taking behavioral treatment is not enough. Individuals who have OCD are usually asked to take Zoloft or Prozac to help calm them during the times that their OCD manifests. However, these medications can cause unwanted side effects such as hallucinations, fainting, and feverish attacks.

Fortunately, OCD can be managed by another alternative. This is through the use of CBD oil. CBD oil has long been in research because doctors have discovered its potential for treating a number of health conditions. Although OCD cannot be fully treated with just CBD oil, it is already known to help manage anxiety disorders that are linked to triggering OCD.

According to doctors, OCD is a symptom of an anxiety disorder, so in looking for an alternative to strong medication, they found that CBD oil is able to calm a person during times of anxiety. A study published in 2011 showed that CBD oil has helped individuals who were exposed to a stimulus that triggers anxiety. In this way, doctors have found a connection between treating anxiety and OCD with the use of CBD oil.

Moreover, a clinical investigation using lab animals showed that a dose of 30mg per kilogram was able to reduce the OCD found in the animals [103]. Although this will not be the same when used on humans, it is still a possible solution for managing or treating OCD [104].

It is a known fact that as women age, their chances of getting osteoporosis increase. Osteoporosis is a health condition wherein the bones of the body become weak which leads to breakage and injury. This condition is often found in elderly individuals.

As the law of life goes, the older a person gets, the weaker the body becomes. This includes a person’s bone health. Naturally, the older a person is, the slower their bone cells are able to repair damaged parts of the bone [105]. So while the body goes through normal wear and tear, the bone becomes unable to keep up with the rate at which bones deteriorate. This leads to weaker bones that are prone to breakage. Contrary to popular belief, osteoporosis does not only occur in women. It just so happens that women are more at risk because this bone condition is caused by changes in hormonal cycles which is common for those who have gone through menopause.

Unfortunately, osteoporosis causes a lot of pain for those who are diagnosed with it. Chronic pain and arthritis are two of the most common effects of having this bone condition. To help those who are experiencing pain, doctors recommend using a wide range of pain relievers as well as therapy sessions to improve bone regeneration.

One of the possible solutions in treating osteoporosis is taking CBD oil, also known as cannabidiol. CBD is known to reduce inflammation because of its anti-inflammatory properties. Although CBD does not purely cure osteoporosis, it helps reduce the development of the condition because it prevents inflammation in the body from occurring. To add to that, CBD can be used as an external source of endocannabinoid which is known to increase the rate in which bone cells help fix broken and damaged bones.

Overall, CBD has a wide range of healthy properties that can aid in strengthening the body even outside osteoporosis.

There are a few famous people who are known to have Parkinson’s disease. There’s Michael J. Fox, Muhammad Ali, and Charles Schultz who are known to have lived with this disease.

Parkinson’s disease [106] is a neurodegenerative disorder which results from the damage and death of neuron cells which are found in the brain. When there are not enough neuron cells or when the neuron cells “die”, a person’s motor skills will be affected. This is why the common symptom of Parkinson’s disease is uncontrollable shaking. An individual’s motor skills will also be affected because of the lack of control the person has when the body starts to act up.

There are cases where Parkinson’s disease becomes complex that strong medication is needed in order to reduce the shaking. However, there is still no cure for Parkinson’s disease as of today. People diagnosed with this condition would have to settle for pain relievers and dopamine agonists that can cause a number of side effects. These side effects include hallucinations, nausea, and insomnia. When not treated properly, these side effects can lead to serious health problems.

CBD oil or cannabidiol is a substance that is seen as a possible medication for Parkinson’s disease. Known for its curable properties in a wide range of health conditions, CBD oil is now a major research focus. As far as Parkinson’s disease is concerned, CBD oil can help give relief to those who are diagnosed with it. It can also help reduce the rate at which neuron cells deteriorate.

Another benefit of using CBD oil is improved motor skills. In a meta-study done in 2017, 90 different investigations showed the effectiveness of CBD oil in managing Parkinson’s disease. It showed that this substance was able to interact with the pathways of the neurons making the tissues stronger and healthier. This increases the chances of having improved motor control.

It might sound unusual, but mad cow disease is a real health condition that can be extremely lethal. Mad cow disease is one kind of prion disease wherein the body has misfolded proteins. Unlike other illnesses that are caused by bacteria or a virus, mad cow disease is caused by a glitch in the proteins found in the human body. This glitch manifests itself by giving proteins a “misfolded” appearance.

Mad cow disease is extremely lethal for two main reasons. One is that it is highly contagious. When one person comes into contact with these glitched proteins, he or she can easily be infected. And what is worse is that there is no identifiable indicator that will tag a person as having mad cow disease. The second reason for this being lethal is that there is no cure. Until today, doctors have found no cure that will stop the spread of prions in the body.

However, there is one substance that has shown an effect on how mad cow disease spreads in the human body. This substance is called cannabidiol. Cannabidiol does not cure mad cow disease, but it is able to lower the rate at which the prions spread to other proteins. Since prions easily affect other proteins and lead them to die or degenerate, having a dosage of cannabidiol will be able to slow down this condition [108].

In a study held in 2007, doctors were able to demonstrate the effect cannabidiol can have on prions. Those that consumed cannabidiol were able to experience a slowed down spread of the virus. In effect, the prions were not able to affect the brain immediately.

But mad cow disease is not the only neurodegenerative disease [107] that cannabidiol can help treat. There are also others involving tissues and cells of the body that could be healed by this substance.

PTSD, also known as a post-traumatic stress disorder, is a psychological disorder wherein the individual is known to experience uneasiness or anxiety as a result of a traumatic experience. These traumatic experiences are usually caused by deaths, illnesses, accidents, and the like. These experiences often trigger a shocking reaction in the individual which can be carried on over the person’s lifetime.

A person diagnosed with PTSD may experience flashbacks, social anxiety, hallucinations, etc. These symptoms show without warning which makes PTSD patients difficult to treat. Add to that the complexity of the traumatic experience and how it was able to affect the individual.

Just like other psychological disorders, PTSD can be managed with the help of antidepressants. However, taking these kinds of medicines can cause a number of side effects [109] that make it difficult for the individual to go about their daily tasks. Although it seems unusual, antidepressants can cause anxiety, mood swings, drowsiness, and even weight gain. Some would argue that taking antidepressants can do more harm than good.

There has been extensive research done in proving the good effects of cannabidiol (CBD) in those who are experiencing PTSD. CBD oil is able to affect the human endocannabinoid system that is related to how the body reacts to trauma. Instead of reinforcing PTSD, CBD oil can help release hormones that give a therapeutic effect on the individual. In this way, their psychological disorder becomes easier to manage.

An advantage CBD oil has over antidepressants is that it does not trigger the same side effects the latter causes. In fact, there is no known side effect that CBD oil creates based on the number of clinical investigations done in the past. To add to that, a recent study was published in 2018 in the Frontline Neuroscience Journal. The study claims that CBD oil is indeed the perfect alternative to antidepressants as a treatment to those who have PTSD.

As people grow older, the chances of having joint pain increase. In fact, as early as adulthood, some people can experience pain in their bones and in their joints. This kind of pain can be considered as rheumatism.

Rheumatism [110] is the general term for any pain caused by inflammation in the joints or in the connective tissues. It is also used to describe arthritis, joint disorders, and other musculoskeletal health conditions. Most of the time, rheumatism is treated by the use of medication or topical products. Medication for rheumatism is often called NSAID or nonsteroidal anti-inflammatory drugs.

Research has found out that the root cause of rheumatism is the production of cytokines. Cytokines is a kind of substance that causes inflammation which is the primary cause of rheumatism [111]. Unfortunately, NSAIDs are not able to interact with cytokines to treat the root cause of rheumatism. However, extensive research shows that CBD or cannabidiol can be used instead of NSAIDS.

CBD oil is known to have a number of health benefits, one of which includes anti-inflammatory properties. In the research done by doctors, CBD oil showed that it interacted with the body’s endocannabinoid system which is responsible for the production of cytokines that cause inflammation. In a number of researches, cytokines were seen to interact with the production of cytokines in such a way that the latter was produced in minimal amounts.

Another advantage of CBD oil is that it is non-psychoactive so it can easily be used in most states in the country. In addition to that, a clinical study conducted in 2009 was able to supplement the claim that CBD oil can easily affect the endocannabinoid system without waiting for a long recovery time. In effect, those who are diagnosed with rheumatism will feel less pain in their joints so they are able to do more important tasks.

When people call someone schizophrenic, most of the time they are referring to a person as “crazy”. Although this can be a misleading term, schizophrenia is actually characterized by having impaired cognitive and behavior functions [112]. This is where the term “crazy” comes from.

Those who are diagnosed with schizophrenia experience a wide range of cognitive and psychological symptoms. Some of these include aggression, lack of emotional responses, hallucinations, and depression. Most of these symptoms can be managed with the use of antipsychotic medication. Antipsychotic medication is one of the most powerful types of drugs. They are used to treat a number of psychological disorders. However, with the strength of these medicines comes with a lot of side effects that could easily be as bad as the actual disorder. Some who are taking antipsychotic medication can result in depression, insomnia, lack of appetite, and many more.

However, cannabidiol or CBD was found by a number of scientific investigations to have the same treating effect for schizophrenia. But the upside to this is that CBD intake does not trigger any of the aforementioned symptoms. And most importantly, it has anti-anxiety and antipsychotic properties that make it an effective treatment to those who have schizophrenia.

In a 2018 clinical study, individuals who were given a dosage of CBD showed lower signs of psychotic symptoms. Another study also showed CBD oil’s efficacy in managing anxiety problems because it was able to modulate the production of hormones triggering anxiety attacks. To add to that, the 2018 study was able to demonstrate an increased cognitive ability for those individuals who were given CBD oil. The methodology for the study was peer-review with a double-blind placebo control to avoid having biases and placebo effect on the individuals.

Overall, CBD oil is a beneficial form of medication and extensive research has already been done to prove this claim.

Other clinical studies point to the beneficial relationship between the endocannabinoid system and cognitive dysfunction. These can include sleep regulation, memory functions [113], emotions, and reward processing. Schizophrenia can impair any or all of these functions.

A hereditary disease condition, sickle cell anemia produces a restriction in blood flow all over the body. Many of the symptoms of sickle cell anemia can be serious if left unmanaged. These can include chronic pain, stunted growth, poor immune function, low energy levels, swelling of the limbs, systemic infections, visual problems, and fatigue.

If left unchecked, sickle cell anemia can lead to life-threatening conditions. Acute chest syndrome, stroke, and hypertension can develop with unmanaged sickle cell anemia. Individuals with sickle cell anemia should observe careful measures to manage their disease and prevent complications.

Hydroxyurea remains one of the most important pharmaceutical treatments for sickle cell anemia. This agent improves the body’s ability to produce hemoglobin. Unfortunately, Hydroxyurea is not free from side effects [114]. Confusion, fever, disorientation, and hallucination are some of the more common manifestations of Hydroxyurea side effects.

The use of CBD for the management of sickle cell anemia is something new in the medical field. Hence, there is not much peer-reviewed scientific evidences that can support the use of such a plant extract on sickle cell anemia. Nevertheless, there are a few that point to CBD oil’s potential as a treatment option for sickle cell anemia.

CBD and cannabinoid products have been shown to be a good alternative to Hydroxyurea. These products can help sickle cell anemia patients manage their symptoms [115] without the risk of adverse reactions. A study in 2016 highlighted the ability of cannabidiol in the management of sickle cell anemia-induced pain.

There is another study in 2017, albeit related to recreational cannabis and not cannabidiol. The study remarked that individuals with sickle cell anemia and who are on recreational cannabis show a reduction in their anemia symptoms. Since recreational cannabis come from the same plant as cannabidiol, it is interesting to assume that CBD oil can also reduce the symptoms of sickle cell anemia.

The human skin serves as the body’s first line of defense; hence, it is subject to many disease processes. Skin conditions are anything that can undermine the integrity in both structure and function of the skin. A good example of a skin condition is acne. This is due to bacterial infections; although some may be due to fungal infections, poor immune function, or systemic diseases.

Any skin condition that is not due to a pathogenic organism is almost always due to inflammation. One of the principal mediators of inflammation in the human body is cytokine. These chemical mediators make the skin appear flushed and reddish while also initiating swelling. In some cases it can cause excessive drying and flaking of the skin. As such, managing inflammation can help address many skin conditions.

Two common manifestations of skin conditions are pain and swelling or inflammation. Current treatments aim to address either or both of these problems. Topical lotions and creams, medications, supplements, and dietary interventions all aim to reduce inflammation. While these treatments work, cannabidiol offers a safer and equally-effective way to manage a host of skin conditions.

Cannabidiol is often indicated in the management of dermatitis. A 2017 clinical evidence supports this claim by virtue of the link between the immune system and the endocannabinoid system.

The study describes that CBD is able to dampen the inflammatory response of the human immune system in a faster and more dramatic fashion. This leads to the reduction of symptoms associated with skin conditions while also promoting faster skin regeneration and healing. The process also does not involve the formation of scars or the development of treatment side effects [116].

A 2005 clinical study showed that hemp seed oil can help improve the symptoms of atopic dermatitis [117]. One of the principal constituents of hemp seed oil is cannabidiol. This makes the study very relevant in bolstering the position of CBD as a viable treatment option for skin conditions.

Sleep disorders are very common. In the United States alone, 1 in 10 individuals suffers from at least one of the types of sleep disorders. Painful medical conditions, anxiety, other psychological conditions, and hormonal imbalances are some of the more common factors that can lead to sleep disorder.

Pharmaceutical agents or sleep agents are the go-to treatment options of people who have sleep disorders. These are chemicals that induce sleep, albeit in an artificial way. Like all synthetic compounds, sleep aids [118] can also produce side effects. Dizziness, blood pressure fluctuations, and difficulty staying awake are some of the more common side effects of these medications.

There is a growing body of evidence pointing to the efficacy of cannabidiol in the management of sleep disorders. The anxiolytic properties of cannabidiol can play a major role in alleviating anxiety-related behaviors. These behaviors can hamper one’s ability to fall asleep. Reducing these anxiety behaviors can lead to a more relaxing experience, allowing the individual to fall asleep faster.

Scientific investigations and clinical trials support the general observation that CBD oil can promote healthy and restful sleep [119] in a more natural manner. In 2017, the Current Psychiatric Reports Journal provided a detailed review of existing clinical researches about CBD and sleep disorders. The review finds a positive relationship between CBD oil use and improved sleep patterns.

The review of clinical and scientific literature revealed that cannabidiol can promote healthier sleep. The plant extract also has the potential to eliminate or manage the causes of insomnia. Cannabidiol is also observed to have the potential to reduce the effects of obstructive sleep apnea. This is a health condition that can threaten the life of the individual and may lead to the development of heart disease.

A 2013 study revealed that CBD oil can help in the establishment of a healthier and more normal sleep and wake cycle. A single dose of 2.5 mg of CBD oil per kilogram of body weight per day is enough to promote a more restful sleep.

Injuries to the spinal cord can produce a wide variety of symptoms. These can have a great impact on the person’s quality of life. Spinal cord injuries come in many types. There are those that are severe like complete spinal cord injury while others are more localized, like hyperextension injuries.

Some of these conditions can produce tetraplegia or quadriplegia. This involves the paralysis of all four limbs and the torso. In paraplegia, there is an impairment or loss in the sensory or motor function of the lower limbs. There’s hemiplegia, too, where the paralysis occurs in only one side (right or left) of the body. Monoplegia refers to the paralysis of one of the limbs only. Triplegia refers to the paralysis of both lower limbs and one of the upper extremities.

In addition to the loss of function of the limbs, chronic pain is a major feature in many cases of spinal cord injuries. The pain can be consistent and ongoing, which requires more powerful analgesics or painkillers. Other individuals with spinal cord injuries can present with depression or anxiety.

Studies prove that CBD oil can improve the quality of life of persons with spinal cord injury. The cannabis extract can also reduce the severity of spinal cord injury-related pain.

The benefits of CBD oil on the management of spinal cord injuries are twofold. First, it provides excellent pain management. Second, it minimizes the psychological effects of SCI by exerting cannabidiol’s anti-anxiety properties.

More recent studies reveal that CBD oil can also improve the motor abilities of individuals after suffering spinal injury. While the test subjects are laboratory rats, a 2012 clinical investigation [120] showed the CBD can facilitate faster healing of spinal cord injury-damaged structures.

Stress is a psychological phenomenon that everyone around the world experiences. If left unmanaged, stress can promote the development of more serious health problems. This can have a negative impact on overall health.

Sleep disorders, mood disorders, migraines, headaches, weakened immune system, high blood pressure, heart disease, insomnia, and depression are some of the health conditions that may result from unmanaged stress.

There are different stress management techniques aimed at reducing the impact of stress on overall health. Cannabidiol is one of the proven effective methods of managing stress levels without causing dependency or other adverse reactions.

There are numerous clinical investigations that support the use of CBD oil in the management of stress.

In 2015, a study revealed that cannabidiol possesses powerful anxiolytic effects. These are comparable to the effects that conventional anxiolytic medications provide, but without the side effects [121].

CBD oil modulates the CB1 and CB2 receptors of the endocannabinoid system. This leads to the more efficient release of serotonin while preventing the secretion of cortisol. The latter is also known as the stress hormone.

A single dose of CBD oil can normalize blood pressure, allowing the body to achieve homeostasis. This also reduces the other physiological symptoms associated with stress [122].

Traumatic brain injuries are often categorized under the broad group of “stroke”. The main pathological feature in stroke or traumatic brain injury is the disruption or interruption of blood supply to the brain. This prevents the delivery of oxygen to the brain, resulting in brain tissue damage.

Blunt force trauma, such as what happens in contact sports, is one of the most common causes of traumatic brain injuries. Regardless of the cause, however, both TBI and stroke will always result in a problem in the individual’s cognitive functions.

Recovering from TBI or stroke involves a variety of treatment approaches. Contemporary treatment regimens require the individual to undergo extensive rehabilitation. The objectives of rehabilitation efforts are to promote cerebral healing while also assisting the individual regain as much independence as possible.

There is a growing body of scientific knowledge indicating the role of CBD oil in the healing of damaged brain tissue after stroke or traumatic brain injury. Clinical trials, including meta-analyses, also show that CBD has the potential to hasten the rate of healing of the human brain.

In 2015, the Neurotherapeutics [123] published a clinical study that focused on the effects of cannabidiol on neuropathy. The research aimed to establish the relationship between cannabidiol and the preservation, rescue, repair, and replacement of lost neurons from strokes and traumatic brain injuries. The results showed that exogenous cannabinoids interacted with the endocannabinoid system of the human body. This is in an effort to resolve issues in brain health while also protecting the brain against further damage.

CBD oil does not 100% heal brain tissue damage. However, it can speed up the process of regeneration in supporting neural structures. It also lays down the foundation for the development of a targeted CBD solution for cerebral injuries in the future.

There are many potential causes and risk factors of irritable bowel syndrome. This is a debilitating disease that features diarrhea, abdominal cramps, bloating, and excessive gas as its principal symptoms. More often than not, individuals with IBS have to adhere to a special diet that can make life more difficult.

Treating irritable bowel disease often involves symptomatic treatment using medications. These do not address the root cause of the problem, which is systemic inflammation. As such, many of these medications produce further discomforts or health problems that can complicate the individual’s life. The exacerbation of gas and bloating can occur because of these medications.

The good thing about CBD is that it can address systemic inflammation without leaving behind unnecessary side effects. In 2016, clinical investigators found that the endocannabinoid system of the human body has a strong link with the gastrointestinal tract.

Researchers observed that CBD can minimize pain, reduce inflammation, and improve issues in the appetite of patients with irritable bowel syndrome. These patients were those from the New York University Medical Center [72].

Additional research studies further support the notion that cannabidiol can constitute a new class of therapeutic agents for the management of irritable bowel syndrome. These studies point to the clinical effectiveness of CBD in addressing systemic inflammation plus the fact that it doesn’t cause side effects.

Clinical evidence also suggests that the human endocannabinoid system plays an important role in the promotion of optimum digestive health. This is one of the most critical implications of the use of CBD in the management of IBS.

Ongoing researches are focusing more on the unique interactions between microbiomes in the human body and the endocannabinoid system. Both of these systems play a role in the maintenance of optimum health of both the immune system and the gastrointestinal tract [73].

These snippets on CBD's associated medical benefits can be expanded upon by visiting our full health effects guide for complete clarity, but now let's see how to buy CBD effectively and look for promo coupon codes to save money when ordering online.

Anyone with online access who has inquired about CBD has experienced an unprecedented proliferation of cannabidiol products to choose from, both locally-made and imported, online or at local shops.  As the number of channels continue to increase, including direct to consumer sales, online retail, natural grocers and speciality brick-and mortor (i.e. vape shops) stores open up the cash register, the amount of cbd oil and cbd-infused product types is breaking records.

Everywhere from Kroger's, Vitamin Shopper, Rite-Aid, CVS and Walgreens to Neiman Marcus, Abercrombie & Fitch, Barney's, Bergdorf Goodman, DSW, American Eage Outfitters and Sephora, CBD is the new Cannabis Big Deal oil.

In order to continue this CBD user guide, let's treat this section of the tutorial as a standalone piece and go into a quick story mode to best describe the easiest ways to find cbd supplements near you.

It was an ordinary night at work for 29-year-old bartender Kendra Cochran. When the broken glass bottle slit her hand all the way down to one of the major nerves, her doctor prescribed painkillers that made her too nauseous to work.

With many patients shunning painkillers, cannabidiol (CBD) oil for pain relief is a hot topic. It has the sex appeal of marijuana with the professional appearance of being available at an expensive supplement store.

As talked about in the introduction, because of CBD’s close relationship to THC, many wonder, “is CBD oil illegal?”, and, “Marijuana isn’t legal in my state, can I still buy CBD supplements?”

The answer is yes. Any CBD oil supplements with a THC content of less than .3% are legal in all 50 states.

But where do you find high-quality CBD supplements in an industry when regulations are still in their infancy?

It’s no secret the beauty industry charges crazy markups for branded products made of cheap materials.

Expensive packaging, “exclusive” formulas, and even social media influencers are all used to sell CBD oil supplements.

In the world of CBD supplements, you don’t necessarily get what you pay for. In 2015, the FDA tested products from legalized west coast states. Every single product tested so low for levels of CBD, the only benefit patients would get from them would be a placebo effect.

When the FDA conducted the same tests a year later on CBD products from other states, the results were the same.

So don’t be fooled by glitzy boxes and glamour shots of supermodels applying the product. Many brands, like Aceso, claim that additives like linalool make their products more bioavailable, meaning easier for your body to use.

But kind of like cosmetics with added fragrances, there is little evidence to show that these additives provide anything more than a nice smell. Yet brands charge as though diluting the CBD in their products is a premium service.

You can buy CBD online. With CBD being legal throughout the U.S., shipping across the country isn’t a problem like it is when THC is involved.

You can even find CBD on Amazon. The only catch is Amazon won’t let sellers put CBD in their product listings.

There’s nothing wrong with hemp oil. It’s great for cooking, but not for relieving pain and other uncomfortable symptoms.

So when you’re looking for CBD on Amazon, be sure hemp extract is one of the first ingredients listed.

If the product you’re looking at doesn’t have the milligrams of hemp extract listed on the nutrition label, you’re looking at hemp oil, not CBD oil.

Amazon won’t let sellers write CBD in their product description, but merchants are often open about CBD content when customers send a direct message.

Some sellers will offer lab reports to show the CBD content of their product. If they have it, always take a look at any lab reports your seller has to offer.

These labs are important because hemp oil is not the only less potent version of CBD oil supplements.

Hemp oil is very nutritious and because many CBD customers are health conscious, manufacturers will leave in the other compounds.

This may be what you’re looking for but if you want higher CBD concentrations, full spectrum oil is the wrong product.

The easiest way to pick out a bottle of hemp oil from CBD oil is the size. Since Hemp seed oil is for cooking, it comes in larger bottles, like the ones you find olive oil in at the grocery store.

Real CBD oil, on the other hand, comes in small, concentrated bottles, usually no bigger than one or two ounces.

You will probably have to try out several products in your quest for quality CBD oil supplements online. That’s why buying them in person may be a better option…

If you live in a state with legalized marijuana, finding quality CBD supplements is as easy as walking into your local dispensary and grabbing some.

But what if you live in a state where medical or recreational marijuana is still illegal. Don’t worry, CBD supplements made from hemp are still readily available.

Smoke shops are one place that often sells CBD oil supplements. There are even some specialty grocery stores and supplement retailers that sell the stuff.

And we’re not the only ones that CBD is marketed to. Pet stores everywhere are jumping on the CBD train and offering products specially curated for dogs and cats.

If you are in a legalized state and buying from a dispensary, be cautious of CBD products that contain THC.

A medical marijuana dispensary will have CBD products most often extracted from strains of plants with much higher THC content than hemp plants.

Some patients may not mind or even prefer THC with the CBD, but many looking for the health benefits don’t want the effects of THC.

Because of the confusion around hemp and CBD oil, some sellers take advantage of this by pricing hemp oil the same as the more expensive CBD oil.

Let’s go over what you should expect to pay when buying CBD oil. While it may not be as much as you think, CBD oil does cost more to extract than hemp oil.

Most reasonably priced CBD oils range from .05¢to .20¢per milligram. But don’t expect to never pay over .20¢per mg.

Some supplement producers will charge as much as customers are willing to spend. This could be up to .60¢or more per mg in some cases.

While .10¢/mg might sound reasonable, keep in mind that this adds up fast. A month’s supply of CBD oil supplements for a patient taking more than one daily dose costs upward of $200-$300 a month.

Yes, a month’s supply of CBD supplements can cost as much as a car payment. When the alternative is a $10 bottle of Advil, many patients can’t justify spending several hundred dollars a month on pain relief.

This is a loaded question. If you were to ask three different industry experts why CBD is so expensive, you’d get three different answers.

Some say it is because of the risk involved with growing and selling hemp. But a lot of manufacturers use outdated, inefficient processes to produce their CBD oil.

Alejandro Bergad, the founder of Green Mountain CBD supplements, says the reason his company is able to sell their products for less than the average retailer is their growing process.

Most producers grow new plants by taking cuttings from full grown “mother” plants and cloning them. This process involves the use of expensive climate control equipment and lighting.

Growers, like Green Mountain, instead grow their crops straight from seed. This reduces both the equipment and labor needed to get those clones into the soil.

“I have been using a pain-relieving CBD salve,” explains bartender Kendra Cochran, “which helps a lot with the pain.” Ms. Cochran now uses several CBD oil supplements for the pain brought on by her work accident.

Kendra and many other patients claim CBD as a godsend in their recovery. With its availability and status as a legal supplement, customers aren’t the only ones lining up to get on the CBD train.

Cannabidiol product prices can vary and often are priced per milligram. According to Highland Pharms, it determined that the average price from six popular brands is $0.15 mg. This number can also vary depending upon how much CBD one uses, the quality of the CBD, and the form that the CBD comes in.

One strategy for those who do not mind a Do It Yourself Project is to make their own CBD oil at home. Thought for Your Penny has a nifty guide on how to do so, and it smartly points out that making one’s own CBD enables users to get more CBD in their mix, and to ensure quality control for a better product. The process requires raw cannabis, which can be found in many places. Keep in mind, the CBD oil recipe is an oil, and thus, it is not meant to be vaped.

Those who would rather purchase their own product can also reduce the costs associated with CBD products by choosing a more economically smart delivery method. There are a number of delivery methods, such as tinctures, edibles, concentrates, capsules, vapes, and topicals. Understanding factors associated with each delivery method, such as how long the type of delivery method lasts, the strength, the general distribution amount needed, and the like, can help users make the most economical decision.

Buyers may also want to consider purchasing products in bulk. Generally, bulk is cheaper in many other contexts, and it just may be so in the CBD context. Users may be able to save a large percentage of the cost associated with CBD by buying the product in bulk, rather than in individual containers. Keep in mind that users should also focus on the quality of the formulas, even if the product comes in bulk form.

Finally, the quality of a CBD product is extremely important, not only for one’s own experience with the product, but also because one is putting money into a product and should receive their monies worth. Thus, users may want to read product reviews and to take the time to research a formula to make sure that it is the right option for their needs.

It should be very evident by now in knowing the CBD sensationalism has taken center stage despite the legal limbo. The last frontier to follow up on requires gathering all credible research and scientific literature detailing how CBD arrived in grand fashion.

While this could be considered the seventh inning stretch in this ultimate CBD product and company review guide, please note nothing here is qualified to act as medical advice. That would be highly illegal and unjust. Always seek additional licensed medical supervision.

However, a proper congratulations is in order for making it this far into a best-in-class CBD resource. After listing the best 30 CBD oils and top 70 ranked companies, along with the medical conditions and complete FAQ components, we are confident every intrigued user and interested buyer is better off having visited the TimesofCBD flagship guidepost on CBD.

And this chart puts into perspective how fierce CBD's popularity has been in comparison to its counterparts of marijuana, cannabis, hemp and even botanical cousin THC.

Not to bore nor overwhelm with galore, but the next link in the chain of command towards which step to take for all CBD enthusiasts and onlookers is going through the medical data.

Much like referenced in the rating lists above, CBD has a long way to go before being fully actualized of all its promise and praise as a therapeutic ingredient, especially with so much conflicting data and often newly-discovered neuroscience findings. Remember, it was less than a year ago the Agriculture Improvement Act of 2018 was passed. The need to go an extra mile by scouring the Internet archives to find out what ‘the world' has discovered thus far about CBD and ambitiously attempt to bring it all under one roof.

“First, elucidation of the chemistry, particularly isolation and synthesis of the active compounds. It turned out there was only one active compound related to psychoactivity, THC. There is a second that had a lot of therapeutic effects called cannabidiol, and we elucidated its structure as well.” […] “I believe the cannabinoids represent a medicinal treasure trove which waits to be discovered.” […] “Mostly this research is being conducted with animals – very little on humans. There are very few clinical trials. It is promising in neuropathic pain, inflammations, anxiety, schizophrenia (with CBD) and many others. When CBD becomes a drug the picture may change.” […] “There is a lot of interest, and I believe this is the third phase of cannabis research. But most people in the States are interested in the first stage, in the THC, in the CBD, in selling it for outrageous prices and trying to make a lot of money out of it.”

Mistrust and misconception fills the CBD market, likely in hopes to bank on any CBD working under the guise of the ‘placebo-effect', but there are plenty of scientific studies surfacing in ‘cannabinoid therapeutics' that are worth-while reads to examine.

The necessary need to stay grounded in sound research and rooted in science-backed clinical data is vital moving forward.

As the final stamp is sealed to send this CBD postcard to the world, here is a complete list of the thoroughly fact-checked and sourced studies used in compiling the raw data behind this ultimate CBD guide:

In addition to these medical studies, this TimesofCBD cannabidiol guide would have not been possible to compile (combined with the 123 medical studies cited in the CBD health benefits section) without the facts, figures and forecasted data used of these top-tier cannabis market research companies who produced analytical-minded insight reports: Brightfield Group, Arcview Market Research, Fact.MR, BDS Analytics, Grand View Research, Adroit Market Research, Mordor Intelligence, Nielsen, Meticulous Research, New Frontier Data, Ellipse Analytics, the matters group, Pew Study, Gallup and of course industry giants NORML, Marijuana Policy Project (MPP), National Cannabis Industry Association (NCIA), Americans for Safe Access, and Cannabis Benchmarks.

The TimesofCBD team would like to a take a second and say #ThankYou for sticking with us throughout this one-of-a-kind guide. As stated, the hope of delivering a holistic understanding of CBD oil and CBD-infused products was our chief aim as well as providing invaluable building blocks to build up a CBD user's awareness. Knowing the who's who and what's what of the CBD world should jumpstart the journey towards buying the best cannabidiol.

The actionable consumer research spelled out here was designed to help clear up any controversies and lingering biases about the cannabis oil megatrend as the preferential shift from prescription drugs to whole plant medicine continues. With the history in mind and a promising futuristic forecast to ponder, a true-to-its-core dedicated CBD buyer's guide highlighting all of the top brand's best CBD products was necessary to formulate.

Disclaimer: As mentioned above, TimesofCBD has been in touch with the majority of the CBD brands mentioned above. Well over half them there have been multiple exchanges in regards to the company policies and product procedures. The lists sourced above represent the most popularly referenced companies and are ever-evolving, subject to change given new announcements, revelations and discoveries.

TimesofCBD is extremely honored to have direct input in the creation of this top CBD oils and best CBD companies list reviews. Without their industry expertise, investigative insights and professional-grade research skills none of this would have been possible. The guide was a total team affair and not possible without a high-degree of collaboration and care.

Researched by: Registered Dietitian, Nutrition by Natalie Written by: Best Selling author, Peter Tzemis Edited by: Canadian Naturopathic Doctor, Dr. Anthony Yores Consulted with: Medical Cannabis writer, Mary Biles Published by: Andrew Expert Quotes and Resourceful Contributions from: Dr. Raphael Mechoulam, Jordan Tishler MD, Javier Hasse, Dr. Mike Hart, Kyle J, Tom A, Pal Pacher, Karyemaître Aliffe, Cecilia Hillard, Dr. David Shurtleff, Ethan Russo MD, Dr. Rahul Khare, ProjectCBD and many others.

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A quick look at Elegance Brands' new Gorilla Hemp CBD energy drink launch and a host of innovative cannabidiol-infused beverages...

Dan Bilzerian's IGNITE CBD company announces release of new Alkaline PH9 Water product and news of more ready-to-drink cannabis-infused beverages...

California Assembly Bill 228 is being considered in California, and if passed by Governor Gavin Newsom, it would permit industrial...

Wisconsin-based company Mother Nature’s Trading Company has released a new cbd/hemp formula. The product, called Cranology, is a combination of...

While last year was big for cannabis, it's 2020 and time to look ahead. More States May Legalize Currently, 33...

It appears that not all marijuana testing laboratories are operated equally. According to a report by the Las Vegas Review...

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